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Entry information : XlPOX01 (PMR-1)
Entry ID 4041
Creation 2006-10-30 (Christophe Dunand)
Last sequence changes 2006-10-30 (Christophe Dunand)
Sequence status complete
Reviewer Filippo Passardi
Last annotation changes 2011-02-01 (Christophe Dunand)
Peroxidase information: XlPOX01 (PMR-1)
Name (synonym) XlPOX01 (PMR-1)
Class Non mammalian vertebrate peroxidase    [Orthogroup: POX001]
Taxonomy Eukaryota Metazoa Chordata Amphibia Pipidae Xenopus
Organism Xenopus laevis (African clawed frog)    [TaxId: 8355 ]
Cellular localisation N/D
Tissue types Liver
Mixed tissues
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value XlPOX01
start..stop		 S start..stop
XlPOX02 1019 0 8..711 8..712
XtPOX02 1012 0 1..711 1..712
MmMPO 871 0 30..711 30..716
OgaMPO 866 0 30..713 30..718
Literature and cross-references XlPOX01 (PMR-1)
Literature Chernokalskaya E., Dubell A.N., Cunningham K.S., Hanson M.N., Dompenciel R.E., Schoenberg D.R. A polysomal ribonuclease involved in the destabilization of albumin mRNA is a novel member of the peroxidase gene family. RNA 4:1537-1548(1998).
Protein ref. UniProtKB:   Q9YH34
Cluster/Prediction ref. UniGene:   Xl.424
Protein sequence: XlPOX01 (PMR-1)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   713 (691)
PWM (Da):   %s   80375.45 (78168.3) Transmb domain:   %s   i12-34o
PI (pH):   %s   8.68 (8.76) Peptide Signal:   %s   cut: 23 range:23-713
Sequence
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*.........1 .........2 .........3 .........4 .........5 .........6 .........7 .........8 .........9 .........0 .........1 .........2
MAPADLWLGV LLILASVQGT ASSYYDGVEE LDNNLILSCT KEAKHLVDTA YKNTRLMLKD RLRRRTVSAS DLMAYFKQPV CSRNAIRAAD YMGTTLQLLS HKLKPFHHRP FNITELLTET  QIDAIYKLTG CAYQHLPSAC QESPYRTITG QCNNRKNPIL GASNTGFTRL LPVVYEDGLS VPRGWTENLP INGFPLPLAR AVSNEIVRFP NENLTLDEGR ALIFMQWGQW TDHDLDLSPE  TPARSTFLEG IDCDTNCAKE PPCFPLKIPP NDPRISNQSD CIPLFRSSPV CTPGSPVREQ INILTSFIDG SQVYGSDWPL AVKLRNNTNQ LGLMAINQRF TDNGLPFLPF ETAEEDFCVL  TNRSSGIPCF LGGDPRVSEQ PGLTAFHTLF VRAHNNIAAR LRELNPRWSG ETLYQEARKI IGGILQKITY KDWLPLLLGS EMAAVLPAYR SYNESVDPRV SNVFTVVFRM GHTLIQPFIY  RLADGYRPLG PEPQIPLHKT FFNSWRVVRE GGIDPLLRGL MANRAKLNRQ NQLVVDELRE RLFVLFKRIG LDLTAINMQR GREHGLPGYN AWRRFCGLSA PSNVNELAAV LNNRNLAEKF 
IKLYGSPENI DIWVGGVAES LVRNGRIGKL LTCLIGNQFR RARDGDRFYY EQPSVFTNEQ RASIERVTLA RVICDNTKIT EVPRNVFLGN RYPRDFVACS RIPTLDLNPW KVA 

Retrieve as FASTA  
Remarks Complete sequence from 1 cDNA and 8 ESTs. Annotated as Polysomal ribonuclease 1. The heme-sulfonium linkage is not present (as typical in myeloperoxidases) Regions defined in NCBI file: pos. 1-713 polysomal ribonuclease 1; pos.143-687 heme peroxidase domain -> apparently no extra ribonuclease domain.