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Entry information : DdPxDo01
Entry ID 4094
Creation 2007-02-15 (Christophe Dunand)
Last sequence changes 2007-02-15 (Christophe Dunand)
Sequence status complete
Reviewer Marcel Zamocky
Last annotation changes 2015-05-13 (Marcel Zamocky)
Peroxidase information: DdPxDo01
Name DdPxDo01
Class Short peroxidockerin    [Orthogroup: PxDo001]
Taxonomy Eukaryota Dictyostelium
Organism Dictyostelium discoideum (Slime mold)    [TaxId: 44689 ]
Cellular localisation Secreted
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value DdPxDo01
start..stop		 S start..stop
PpalPxDo01 615 0 9..530 12..534
PlmaPxDo01 377 2.22e-122 23..529 96..586
BmaPxDo01 342 1.99e-110 23..529 22..510
LspPxDo01 338 3.42e-109 23..529 144..659
Literature and cross-references DdPxDo01
Literature #1 Escalante R., Iranfar N., Sastre L., Loomis W.F. Identification of genes dependent on the MADS box transcription factor SrfA in Dictyostelium discoideum development. Eukaryot. Cell 3:564-566(2004).
#2 Zamocky M. et al. The peroxidase-cyclooxygenase superfamily: reconstructed evolution of critical enzymes of the innate immune system. Proteins 72:589-605.
Protein ref. GenPept:   AAQ98871.1 UniProtKB:   Q6TMK4
DNA ref. GenBank:   AY392429
Protein sequence: DdPxDo01
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   531 (510)
PWM (Da):   %s   60630.09 (58220.7)  
PI (pH):   %s   6.2 (6.03) Peptide Signal:   %s   cut: 22 range:22-531
Sequence
Send to BLAST
Send to Peroxiscan
*.........1 .........2 .........3 .........4 .........5 .........6 .........7 .........8 .........9 .........0 .........1 .........2
MRLNLISFFI IFTILVSISN SQEFRSYTGE GNNKQNPKQG SIFTPFIRLA NPIKFNKNGF PNITNQPSRA ISNIIFDQQT HIGSKEHLTD MFNMWGQFLI HNMALSKPEP NSWPIKVPKC  DQYFDPACIG NKTMNYFRTR ATEVPCDVGK TVVDEDGKCY EQINSLGSYI DGNVLYGNSE EICKNLRSLS GGEMKMTVTD VGDLPPKNVP GVPMDNDANL FPIDQLYSVG ERRGNENPGL  LSIHTLLLRD HNRLARKFAR LHPEWDDERV FQQSRSCIIE QIQKITYDEY LPTTLGSFPS YTGYDANVNA QVSNEFTTTA FRFGHSEVGP FMEYYSENGT RLQPLPIKFS YFNPHALNRG  VEPLIRGLII NEEENIDIYM ISDLRNFLFG KPGQGGLDLA SRNLQRNRDH GIPPYNSLRR QLGLRPVQTW SDITSDPQIQ NRLKNAYKSV DDIDSYVGGL AEDHMEGSCV GQTFYLIIYE 
QFFRTRAGDR FWYETPEMRM VNRECETTTF AEVIKRTTSN IGYVQPNVFR K 

Retrieve as FASTA  
Remarks Complete sequence from genomic and 3 ESTs (C93038, BJ379640, BJ383224). Similar with bacterial peroxidockerins. Signal sequence for secretion predicted with SignalP 4.1 Server: max. cleavage probability between pos.21 and 22; 2 introns predicted with FGENESH both on N-terminus, the peroxidase domain is intronless (support for LGT).