Entry information : Hs2CysPrx01 (PAG / NKEF A / PrxI)
Entry ID 4501
Creation 2007-01-25 (Nicolas Rouhier)
Last sequence changes 2010-12-03 (Myriam Duval (Scipio))
Sequence status complete
Reviewer Filippo Passardi
Last annotation changes 2010-12-03 (Myriam Duval (Scipio))
Peroxidase information: Hs2CysPrx01 (PAG / NKEF A / PrxI)
Name (synonym) Hs2CysPrx01 (PAG / NKEF A / PrxI)
Class Typical 2-Cysteine peroxiredoxin    [Orthogroup: 2CysPrx001]
Taxonomy Eukaryota Metazoa Chordata Mammalia Hominidae Homo
Organism Homo sapiens (human)    [TaxId: 9606 ]
Cellular localisation N/D
Tissue type Mixed tissues
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value Hs2CysPrx01
start..stop
S start..stop
Ptro2CysPrx01-1 412 1.36e-149 1..199 1..199
Pabe2CysPrx01 411 2.37e-149 1..199 1..199
Mnem2CysPrx 411 2.37e-149 1..199 1..199
Mmul2CysPrx01 411 2.37e-149 1..199 1..199
Gene structure Fichierperl './assets/cgi-bin/draw_exon.pl' '4501' 'complement(join(45977001..45977086,45980179..45980309,45980545..45980667,45981326..45981479,45984610..45984715))' Exons
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 45984610..45984715 104 N° 2 45981326..45981479 152 N° 3 45980545..45980667 121 N° 4 45980179..45980309 129
N° 5 45977001..45977086 84  
complement(join(45977001..45977086,45980179..45980309,45980545..45980667,4598132 6..45981479,45984610..45984715))


exon

Literature and cross-references Hs2CysPrx01 (PAG / NKEF A / PrxI)
Literature Prosperi M.T., Ferbus D., Karczinski I., Goubin G. A human cDNA corresponding to a gene overexpressed during cell proliferation encodes a product sharing homology with amoebic and bacterial proteins. J. Biol. Chem. 268:11050-11056(1993).
Protein ref. UniProtKB:   Q06830
DNA ref. GenBank:   NC_000001.1 (45984715..45977001)
mRNA ref. GenBank:   CAA48137
Cluster/Prediction ref. UniGene:   Hs.180909
Protein sequence: Hs2CysPrx01 (PAG / NKEF A / PrxI)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   199
PWM (Da):   %s   21968.19 Transmb domain:   %s   i52-74o89-111i132-154o169-191i212-234o244-266i305-324o410-432i
PI (pH):   %s   7.96
Sequence
Send to BLAST
Send to Peroxiscan
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
ADEGISF
RGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGVCPAGWKPGSDTIKPDVQKSKEYFSKQK

Retrieve as FASTA  
Remarks Complete sequence from Genomic (chromo 1, 4 introns), 16 mRNA and 2795 ESTs.
DNA
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGTCTTCAGGAAATGCTAAAATTGGGCACCCTGCCCCCAACTTCAAAGCCACAGCTGTTATGCCAGATGGTCAGTTTAAAGATATCAGCCTGTCTGACTACAAAGGTGAGAGAATTAAC
ACTGGGCTCATTGAGATGGAGTTATTTTATATTCTAGGGGTGGCTTGTTAGATTTGTGTCAATGTTGTTTGACTGTAAAATGTTTTGTCTCCTAGGAAGAAGTATTTAGGTTGTTACCTT
CATGTTGAAGTGGTGATTATCAAGTGATTACAGGGTATATATCCTAGGACCAAACCACTTCTGGAGAAACCACATGCTTCATTATGTCTGGACATACTAGCTCAATTATCTTTTCAGTAT
TCCTCGTCTATTTTCTTTCTTTATTTTTATTTTTGAGACAGGGTCTCATTCTGTCACCCAGGCTGGAGTGCAGTGGCGCAGTCATGGCTCACTGCAGCCTCTACCTCTCTGGGCTCAGGT
GGTCCTCCTACCTCAGCCTCCCAAGTAGCTGGGACTGTAGGGGCATGCTGCCATGCCTGGCTAATTTTTGTACTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTTTTGCTCTTGTTGC
CCAGGCTAGAGTGCAATGGCGTGATCTCGGCTCACCACAACCTCCACTGCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGCGCCATCATGCCT
GGCTAATTTTTTTTTGTATTTTTAGTAGAGACGGGGTTTCTCCATGGTGGTCAGGCTGGTCTCGAACTCCTGACCTCAGATGATCCGCCCACCTCGGCGTCCCAAAATGCTGGGATTACA
GGCATGAGCCACCACGCCTGGCTTAATTTTTGTACTTTTTGTAGAGCTGGGCGCCATGTTGCCCAGGCTGGTCTCCAACTCCTGGGCTCAAGCCCTCTGCCTGCCCTAGCCTTTCAAAGT
GCTGGGATAACAGGTGTGAGCCACTGCCTCTGGCCCTCCTCTATTTTATTATTGGAGAAATACTCATTATCTCTTGTTATAAGAGACATTCTACATTTAAAGTCTCAGAGCTCACTCAAA
TCTCTGGAGCTGTGACACTGCTCGTTCAGTTTGTTTGGGTCACGTATATATCACAGCTGTTAATATTAGGCTGAGGGCTAGGCACTTTCCCTTGCCTGTTTTGACCCCGGAGGAGAGTTG
ATATTACAGATGGAACAACTCTCCTTTCTGTTGTCATAGTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTTTGTCGCCCAGGCTAGAGTGCAGTGGTGCGATCTCAGCTCAC
TGCAAGCTCCGCCTTCTGGGTTCATGCCATTCTCAGGCCTCAGCCTCTTGAGTAGCTGGGACTACAGGCGCCCGCAACCATGCTTGGCTAATTTTTTTGTATTTTTAGTAGAGACGGGGT
TTCACCATGTTTGCCAGGATGGTCTCGATCTCCTGACCTTGTGATCCGCCTGCCTTGGCCTCCCAAAGTTCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCCTCTGTTGTCATAGTTT
CATGCAGACACTTGGCAAGTTCTGTTGAGGCTCCTCCTTTCTTTACCTTGTAGTTCCAGAGCAGCTCGATCTCCTGGGACAGTTGAGGATATAGATTCCTTAGAATGCTAACCTGAAACT
CAGGTGTCAAGTGTCCTTTTCTCAGTGGTGTAGCATTAGTCCCTGGAGTTAGTTTTTGGTAGAACATTTGACTAGGTTTCCTGACATAATCACACTTTGTTCTTGGGGCTTCTCCCAGCA
AACAAGGTAAGTTGCACCATAGGGAGGTGACCTGGGCCCAGGGGTATAAGCAGGAGGTCTAGGAGGAGCTGTTCTCTGCCCTCCAGAGCTTGACCTGCTGAGGCCCCAAAGTGCTTGTTA
GGCAAAGCTGGAAGGGTTGTTTAGATGAGTTAGTTTCCAGTGATACTGCAAAGTGGTAAATGTCAAAAAGGGCTGCTTGTTTGGCTTTTTTTTTTTTTTTTTGAGGTGGAATTTTGATCT
TGTCGCACAGGCTGTAGTGCAGTGGCATGATCTCAGGTCACTGCGACCTCCATCTCCCCGGTTCAAGTGATTCTCCTGGCTCAGCCTCCCCAGTAGCTGAGATTTCAGGCCCCCGCTGTC
ACACCCAGCTAATTTTTGTATTTTTAGTAGAGACATGTTTTACCATGTTGGTCAGCCTGGTCTTGAACTCCTGACCTCAGGTGATCCACCCGCCTCGGCCTCCCAAACTGCCTCCCAAAC
TGCTGGGATTACAGACGTCAGCCACCATGCCACCACACCCAGCCTGTTTGACTTTTCAAACATTGCTGCTACCTGGAAATGAGTGAATATTTGGAATTGTTCTAGTATTTAAGCCTGGTG
GGTGTGGCGAGAAGGCTGCCTGGCCAGTTTGAAGATCTGTTATTTCAGTGGTTAATCCCAGTGACTTCATTAAAATTGCAGCTAGAAGTTCTGTTACTCACTAGTACTTTTGTCTTTTCT
GTCTCTCTCTGTCTCCCTCTTTCTCTCTCTCTCTCTGTGTATATGTATATATATATTTCTGTTGTTTTGAGACAGTCTTGCTGTGTTGCCCAGGCTGGCCTCAAACTCCTGGGGTCAAGG
GATCCTCCCACCTCAGCCTCCCAAGTAGCTGGGACTACAGACACGCACCACTGTGCCTGGCTTAAAATTTTTCCTGTCCTGTCAGGCACGTTAGGAACACATGTGATCACTTAAACCATG
CTTGTTCCATTACTATGGTTCATCACGGGAGAAGTGCAAAGGCTGTGACTTCTTATTGGTGTCTTATCTCTACAGCAGAGGAGTACTGCAATTCAGCTTTCTCTGGGTATTGTTAAGCAT
TGGCATTAGGCCATGCTTATAAGTGCATCCTTGCTTTTGCTATCTTTGGAGAACTTGGTGTTTATGTTAATTTTAGCCACTCAGAAAAGATCAAAATTAGACTGAACAGTGTTTACTCTG
TATTGGTAGCTATGACATGGAGGCAGGAGAATAAAGTATGGGATTGGAAGTTTTTTTCATTCAGGTATTCCTAATGCACCAGGTTCTAAAAGTAGCTTCTAGGAGACATCTGTATTGAGC
ATCTTGGCAGTTAGTGGTTATTGTGTCAGCCATCAACTTGCTTCTTTTTGTATAGGAAAATATAAAGCAAGGAAGTCTGTGTCAAATGCTAACCATGACTCCGATTTTCCCCCCAGGAGA
AAATATGTTGTGTTCTTCTTTTACCCTCTTGACTTCACCTTTGTGTGCCCCACGGAGATCATTGCTTTCAGTGATAGGGCAGAAGAATTTAAGAAACTCAACTGCCAAGTGATTGGTGCT
TCTGTGGATTCTCACTTCTGTCATCTAGCATG
GTAAATCTCTTGGTCTATTTGGCATGTGAACTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTTTGTCGCCCAGGCTGGA
GTGCAGTGGTGTGATCTCCGCTCACTTCAAGCTCTGCCTCCCAGTTTCACGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCTGCCACCATACCTGGCTAATTTT
TTGTATTTTCAGTAGAGACGGTGTTTCACCGTGTTAGTCAGGATGTTCTTGATCTCCTGACCTCGTGATCTGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGC
ACCTGGCTGGCATGTGAACTTTTAAAACAGCAACTGGGAAGCTTTGGCAATAGACTTTCAAGTATTGCCTTCTCATTGAAGGGAGTGCAAAGTCTGACTTTCTCTTATTGCTCTCATGAC
CTGGCAGCAGAGAAGAAGCAGCTTCAATTGCAGTTGAGTGTACCCTAGTGACCTACCTTAACTGTTCTCAGCATTCACTTTATTGCTGGAAAACGGAAAAAAAACAGTCTTTTTGGAAAG
TTAGATTAGGAATATGGGAAAGGGGAAAGAGGAATGCGTACAGTCAAGTCAAGAGTTTGAATGTAACTGTATGTTTGCCTTTTGCCATAGGGGGTCAATACACCTAAGAAACAAGGAGGA
CTGGGACCCATGAACATTCCTTTGGTATCAGACCCGAAGCGCACCATTGCTCAGGATTATGGGGTCTTAAAGGCTGATGAAGGCATCTCGTTCAG
GTATGTCATCAGGACAAGTATCCAG
TTGGCTGAAAGCCTTTTATTTGGAGAGATCTAGAGCCCTGATCTGTAGAGACTCCTTGTCATTTCATTCCTTTATGCAGGGGCCTCCTCACTAAGGCCAGGCCAGTAGGAGTGTGGAGAC
CAGTCCATTTCCTTCAGGCTTCAAGCCTCTGTATTCTAACAAAGCACATCTCTAAACCTGTATTGCTTTTCCTTTCATCTCTTTTCCCAGGGGGGCCTTTTTATCATTGATGATAAGGGT
ATTCTTCGGCAGATCACTGTAAATGACCTCCCTGTTGGCCGCTCTGTGGATGAGACTTTGAGACTAGTTCAGGCCTTCCAGTTCACTGACAAACATGGGGAAG
GTAAGCCATCTGTCTGA
TAACAGGACAACAGAGTGGTGGTATGAAGGGGTGGGTTGCCCCTTCACACCTGTGGGTGTTTCTCGTTAGGTGGAATGAGAGACTTGGAAAAAGACACGTAGACAAAGTATAGAGAAAGA
AATAAGGGGGCCCAGGGGACCAGTGTTCAGCATACAGAGGATCCCGCCGGCCTCTGAGTTCCCTTAGTATTTATTGATCATTCTTGGGTGTTTCTCGGAGAGGGGGATGTGGCAGGGTCA
TAGGATAATAGTGGAGAGAAGGTCAGCAGATAAACACGTGAACAAAGGTCTCTGCATCATGAACAAGGTAAAGAATTAAGTGCTGTGCTTTAGATGTGCATACACATAAACATCTCAATG
CCTTAAAGAGCAGTATTGCTGCCCGCATGTCCCACCTCCACCCCTGAGGCGGTTTTCCCCTGTCTCAGTAGATGGAACATACAATTGGGTTTTACACTGAGACATTCCATTGCCCAGGGA
CTGGCTGGAGACAGATGCCTTCCTCTTGTCTCAACTGCAAAGAGGCGTTCCTTCCTCTTTTACTAATCCTCCTTAGCACAGGGTGTCAGGCTGGGGGACCCCGGTCAGGTCTTTCCCTTC
CCACGAGGCCATATTTCAGACTATCACATGGGGAGAAACCTTGGACAATACCTGGGTTTCCTAGGCAGAGGTCCCTGTGGCCTTCCGCAGTGTTTGTGTCCCCGGATACTTGAGATTAGG
GAGTGGTGATGACTCTTAAAACGAGCATGCTGCCTTCAAGCATTTGTTTTAACAAAGCATATCTTGCACAGCCCTTAATCCATTTAACCCTGAGTTGACACAGCACATGTTTCAGGGAGC
ACAGGGTTGGGGATAAGGTTACAGATTAACAGCATCTCAAGGCAGAAGAATTTTTCTTAGTACAGAACAAAATGGAGTCTCCTCTGTCTACTTCTTTCTACACAGAGACAGTAACAATCT
GATCTCTCTTTTCCCCACAGTGGTAGAATGGGAAAGATAGTAGGAACAGAAGCTACCAAATAAGAAAATGGGTATCTCTCTTCATAAATTGAAGCCCCTGGATTACAGTGTGTTGTGAGG
GTGAGGGTAATGGAAAAGCTTGGGAAGGAGAATATAAAGGCTTTTTATTCAAAGTATACATACTCCTCTCTTCTGTCCTGCTCATTTAGAATCAGTCACTCCCAAAGATCTAACTTACTG
AATGTAGGATGATCTCACAGATGTATTAGGGCAAAACAAAATGGTTGGGAATCACCTCTAGAGATAAAGCATGCCATTTTTTAAATAACTTTATTGAGAGAAGAGGTTAATCCATATAGT
TCATATTTTTATTTATTTATTTATTTTTTGCAAGATGGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCAGTCTTGGCTCACTGCAACCTCCGCCTCCCCTGAGCCATTGCGC
CCAGCCCAGACTAGCTTTCTAAGGCCTATTTCAGCTCTGATCTTGTAATTTAAAGGAAATGAAGTTATTAGAGTCTGGATTAGTGGTGTATGTTTGGGAAGACCCAAAGGTGCTAGCTTG
GCTAGCACCAAGTAATCTTTTTACAGGGATTAGAGTCTGATTATATAGGGATCAGTGAGCACTGATAACCAAGAGGTACCCTTTGCAGAAGGATGTGTGGGCAGTTAGCCTGGACAGATG
ACACATGGCTCAGCTGACACCTGCTGAGACTGCCCCCTTGTGGGAGATGAGGTTCAGCATTAAGAAGGAGGCAGCAGTGGCAAAGTAGGCCCTTTAACTGGACTTTCCTAGGAACCTACA
TATAGGTTAGTCTCCTGAACCCAGGCTTTCATAACTCAGAAGCTTGCTTCTTCAGACTCTGTTGGTCTCTGCTGCTTCCCATCCCACTGGAACATGTACAGCCTCTTAAATAGGTACCAT
TTAAGAGCCAATGAATGCCAAACACTTTTTTTTTTTGAGACAGAGTCTTGTTTTGTCGCCCAGACTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAGCCTCCACCTCCTGGGTTCAAG
TGATTCTCTTGCCTCAGCCTCCTGAGTAGCTAGGACTACAGGGGTCCACCACCACGCCCCACTATTTTTGTATAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCATGAACCCC
GGAGGTGGAGCTTGCAGTGAGCTGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAATGTGAGACTGTCTCAAAAATTAGCCAGGTGTGGTGGTGGGCGCCTGTAATCCTAGCTATTTG
GGAGGCTGATGCAGGAGAATCGCTTGAACCCGGGAGACCGAGGTTGCAGTGAGACGGAGGTGGAGATTGCGCCACCGTACTCCAGCCTGGGCAACAGAGGGAGACTCCATCTCAAAAAAA
AAAAAAAAAAAAAAAAAAAAGAAAAATAAGAGATTAGTCCCCTTGCCTCATTTTCTTCAGGCTAGCCTGAGGCACATTCTTAGGCATTGTCAGGAAAAGGTTGAAGGCTGTGCTTTCTGT
ATAAATCTATGAAAAATTTCAAACTCTGCCTTTTGCTTACCAAGGGGTAGATGGCAGTTACTTAATGAAACAAGCGGGGGCTTCTGTTAAGTTCTTGATCCTTTATAAGGTTCAGGCTAT
CCAGTTTGGTAGAGTTAGAAGAATGCTGAGAAGGCAGACTGAGTTTGCTGTCTTCAGAGCTCTGAAGGGCTGTCAGAAACAGTTTAGTGTTAAGGGTTTACATAGTCCTATGTGTGTCGT
TTATTTAGCTTTTTTTTCCCCTTAAGGATTAGAGAGTGTTGGCAAATTATTTAAACTTTGCCTTTTTTTGTGGAAAATTTAAATTTCAAGTGCTACATGAATAAATTAGGCATGATAGTA
TCTTAAGGCTGTGGTGATGATTATATGTTTGTAAAATGGTTAGCTCATACTAAAAGGGTGAATGATCTAAGACTGATTGCAGGGGTAGGTTTCCTGGTATCTGAGTGTTCAGGTGCAGAA
CTGGTTTTGTCCATAGGAGAATGGTGGTGCATACCATTGAGAAGGTTATTAATTAGTGGTGCCTTTCTCTTGCAGTGTGTGCCCAGCTGGCTGGAAACCTGGCAGTGATACCATCAAGCC
TGATGTCCAAAAGAGCAAAGAATATTTCTCCAAGCAGAAGTGA

Retrieve as FASTA  
CDS
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGTCTTCAGGAAATGCTAAAATTGGGCACCCTGCCCCCAACTTCAAAGCCACAGCTGTTATGCCAGATGGTCAGTTTAAAGATATCAGCCTGTCTGACTACAAAGGAAAATATGTTGTG
TTCTTCTTTTACCCTCTTGACTTCACCTTTGTGTGCCCCACGGAGATCATTGCTTTCAGTGATAGGGCAGAAGAATTTAAGAAACTCAACTGCCAAGTGATTGGTGCTTCTGTGGATTCT
CACTTCTGTCATCTAGCATG
GGTCAATACACCTAAGAAACAAGGAGGACTGGGACCCATGAACATTCCTTTGGTATCAGACCCGAAGCGCACCATTGCTCAGGATTATGGGGTCTTAAAG
GCTGATGAAGGCATCTCGTTCAG
GGGCCTTTTTATCATTGATGATAAGGGTATTCTTCGGCAGATCACTGTAAATGACCTCCCTGTTGGCCGCTCTGTGGATGAGACTTTGAGACTAGTT
CAGGCCTTCCAGTTCACTGACAAACATGGGGAAG
TGTGCCCAGCTGGCTGGAAACCTGGCAGTGATACCATCAAGCCTGATGTCCAAAAGAGCAAAGAATATTTCTCCAAGCAGAAGTGA

Retrieve as FASTA