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Entry information : Ptro2CysPrx02-1 (PRDX2 / Ptro2CysPrx02-1)
Entry ID 6551
Creation 2009-01-29 (Christophe Dunand)
Last sequence changes 2010-11-23 (Myriam Duval (Scipio))
Sequence status complete
Reviewer Christophe Dunand
Last annotation changes 2010-12-21 (Christophe Dunand)
Peroxidase information: Ptro2CysPrx02-1 (PRDX2 / Ptro2CysPrx02-1)
Name (synonym) Ptro2CysPrx02-1 (PRDX2 / Ptro2CysPrx02-1)
Class Typical 2-Cysteine peroxiredoxin    [Orthogroup: 2CysPrx001]
Taxonomy Eukaryota Metazoa Chordata Mammalia Hominidae Pan
Organism Pan troglodytes (chimpanzee)    [TaxId: 9598 ]
Cellular localisation N/D
Tissue type Brain
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value Ptro2CysPrx02-1
start..stop		 S start..stop
Mmul2CysPrx02 407 6.27e-148 1..198 1..198
Mfa2CysPrx02 407 6.27e-148 1..198 1..198
Hs2CysPrx02 407 6.27e-148 1..198 1..198
Ggo2CysPrx02 407 6.27e-148 1..198 1..198
Gene structure Fichier Exons►
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 13166302..13166404 101 N° 2 13166059..13166212 152 N° 3 13165320..13165442 121 N° 4 13165002..13165132 129
N° 5 13162829..13162914 84  
complement(join(13162829..13162914,13165002..13165132,13165320..13165442,1316605 9..13166212,13166302..13166404))


exon

Literature and cross-references Ptro2CysPrx02-1 (PRDX2 / Ptro2CysPrx02-1)
Literature Hellmann,I., Zollner,S., Enard,W., Ebersberger,I., Nickel,B. and Paabo,S. Selection on human genes as revealed by comparisons to chimpanzee cDNA. Genome Res. 13 (5), 831-837 (2003).
DNA ref. GenBank:   NC_006486.2 (13166404..13162829)
mRNA ref. GenBank:   XM_524127.2
EST ref. GenBank:   CB294573.1
Protein sequence: Ptro2CysPrx02-1 (PRDX2 / Ptro2CysPrx02-1)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   198 (307)
PWM (Da):   %s   21764.2 (33546.3)  
PI (pH):   %s   5.36 (4.48) Peptide Signal:   %s   cut: 28 range:28-334
Sequence
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Send to Peroxiscan
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDE
ALRLVQAFQYTDEHGVCPAGWKPGSDTIKPNVDDSKEYFSKHN

Retrieve as FASTA  
Remarks Complete sequence from genomic (chromo 19, 4 introns) and 5 ESTs. Isolate="Yerkes chimp pedigree #C0471 (Clint)".
DNA ►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGGCCTCCGGTAACGCGCGCATCGGAAAGCCAGCCCCTGACTTCAAGGCCACAGCGGTGGTTGATGGCGCCTTCAAAGAGGTGAAGCTGTCGGACTACAAAGGTGAGCGCCGCCCGGAG
GGGGCCCAGGTAGAAGCGGGGCCGTGCATGAGAGAAGCTGGGCCCTAACTCCTCTGTGTCCCTCCTCCCCAGGGGGAAGTACGTGGTCCTCTTTTTCTACCCTCTGGACTTCACTTTTGT
GTGCCCCACCGAGATCATCGCGTTCAGCAACCGTGCCGAGGACTTCCGCAAGCTGGGCTGTGAAGTGCTGGGCGTCTCGGTGGACTCTCAGTTCACCCACCTGGCTTGGTATGAGCAGGG
GCCAAAGAGGGAGGTTGCAGCTAAGCTCACACCCTCGGGTCCCAGCTGTGTGGCTTCGTGGCCATTGCTCAACCTCTGGAACCTGCGTTTCCCCATCGTGAAAATAATGGAAACATCTCC
CGCCAAGTCTTTAAGGATGATGACAGTAATTAGCATTTGACAACTAGTTGCCTGGCATATAGAGTTGCAGATGCAACTCAGATGCAACTCTATCTACTCTATCTACTTAGTTCCCAGGAG
GGAGGCTGTGCTGCCCTATTTCATGAAGATGGAAACTCCAGTTCACCGAAGTGAAGGGCTGTACCCCATGACACAGCTAGAGGAGGATGGGGACTCTTAACACGGGCTCTCTGCTGGGTG
ATGCTGCAAGTTACAAGCACATGTGAAGCCACTTAGCTGGAGCTGTGCCTCTCAAACTCAGTCTTCCCAGCCGTGGGGATACAGTCCTTGCACCCAACCCAGGGTGGGGTGGGTGAGGCT
CCCAGCAGCCTACTCTAAAGCCCCTTATCTCTGGCCTCCAGTGCTTATCACATTGGGCCCACAGGGTGAGGACCCTGCTGTGCCAGGCATCCTGAGGCCCCAACTCTGTCTCCCCTACTC
CCAGGAGATCAACACCCCCCGGAAAGAGGGAGGCTTGGGCCCCCTGAACATCCCCCTGCTTGCTGACGTGACCAGACGCTTGTCTGAGGATTACGGCGTGCTGAAAACAGATGAGGGCAT
TGCCTACAGGTACTGTGGGACCCTCAGCCCGGCTCAGGGAGCGCCCTGCCCCCCATTCCTGTGATGCTGGGACCACTCCTGTACAATGTCTTCTCTGCCCCCAGCCCTGTGGCTAGCAGC
GGGTGGTTGGTAGTCCCTTCCTTGTCTCTGGCAGTGGGAGCTACCAGCTCCTCACTGGGAACCCTGATGTCTTCAGGGGGGCCTCTTTATCATCGATGGCAAGGGTGTCCTTCGCCAGAT
CACTGTTAATGATTTGCCTGTGGGACGCTCCGTGGATGAGGCTCTGCGGCTGGTCCAGGCCTTCCAGTACACAGACGAGCATGGGGAAGGTGAGCAGATACACACAGGACACATGGGTAC
ATACTGAGCGCCTCCGTCACTCATGCAAACATTCACTGCCTGTCCTCTTACCTGTCCAGATGGGTGTTAGGGCCCCAAAGAAGATTCAGCTCAGGGCTTTGTCTGCAGGATGTTTCTAAT
GTGGTAGGAGACAAATAATGCCTGACATTCAACCAAGGTGGACAAAGGGGCTGGGCTCAGTGGCTTACGGTTGTAATGCCAGCACTTTGGGAAGCTGTGGCAGGTGGATCACCTGAGGTC
AGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCCGTCTCCACTAAGAACACAAAAAATTAGCTGGGCGTGGTGGCGCACACTTGTAATCCCAGCTACTTGAGAGACTGAGGCAGG
AGTTCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCATTGTACTCCAGCTTGGGCAACAGAGCAAAACTCAGTCTCAAAAAAAAAAAAAAAAAATTAGCTTGGTTT
GTGAAGCATGCCTATAGTCCCAGCTACTCAGGAGGCTGAGGCTGGAGGATCACTTGAGCCTGGGAGGTCAAGGCTGCAGTAAGCTGTGATCGCACCACTGCACTCCAGCCTGGGCGCCAG
TGTGAGACTCCATCTCAAAAACAACAACAACAAAAAAGCCTGTAGGGGTGGGGCAGAGGGACAAAGATGGGATTAAAGGAGCCAAAAAGACAGGAAGATGCTGTGTCTCATGCCTGTAGA
TAGTTCCACCTACTCTGGAGAGTGAGGCAGAAGATTGCTTAGGCCCAGGAATTTGAGTCGAGCCTAGGCAACATAGCAATACCCCATCTCTTTTTTTTTTTTTTTTTTTTTAAGAGATGG
GGTATTGGTCAAAAAAAAAAAAAAAAAAAAAAGAGGCCAGATGCAGTGGCTCACACCTGTAATCCCAGCATTTTGGGAGGCCTAGGCGGGTGGATCACCTGAGGTCGGGAGTTCGAGACT
AGCTTGACCGACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCCAGCCTGGTGGTGCATGCCTGTAATCCCCGCTACTTGGGAGGCTGAGGCAAGAGAATCGTTTGAAGCT
GAGAGGCGGAGGTTGCAGTGAGCTGAGATAGCGCCATTGCACTCCAGCCTGGGCAACAGAGCAAGACTTCATCTTAAAAAAAAAAAGAAAAGAAAAAAAGAAGAAAAAGGAGAGCTGGGT
GGCAAAAAGAAATTGAAGAATTAAGAGTACGAAAAACACCAGCTAGAAAATACTGAACTTGGCCAGGTGTAGTGGCTCACGCCTGTAATCCTAGCACTTTGGGAGGCCAAGGTGGGTGGA
TCACCTGAAGTCAGGAGTTCGAGATCAGCCTGACCAATATGGTGAAACCCTGTCTCTGCTAAAAGTACCAAAAAATTAGCAGGGTGTGGTGGCGGGCACTTGTAGTCCCAGCTACTCAGG
AGGCTAAGGCAGGAGAATCACTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCGAGATCACGCCATTGCACTCCAGCCTGGGCAACAGAGCAGGACTCTGTCTCAAAAAAAAAAAAAAGA
AAGAAAAAAGAAGAAAAGAAAAAGAGAAACTACTGAACTTGGCTAGGCATGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGACGGGCAGATGACTTGAGGTCAGGAGTTC
AAGACAAGCGTGACTAACATGGTCTCTACCAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCACCCCTGTAATTCCAGCTACTTGGGAGTCTGGGGCATGAGAATCCCTTGAACCCAGG
AGGGAGAGGTTGCATGAGCTCAGATCATGCTACTGTACTTCAGCCTGGGCAACAGAGCAAGACTCTGTCTCAAAAAAAAAAAGAAAAAGAAAAAGAAAAAATACTGAACTGGGCTTGGAG
GGCTTATCTTAATATCCACATTCCTGGTCCTGGACCACTTGCTTCCAGCATTTTCTTCTGCAACACAGGCCCTTGCTTTGCTTCACCTTGAACCTGGGGCTGTAGCCTTCATGTGCATCC
TTGTGTCTTCCCACAGTTTTTGTCCCGCTGGCTGGAAGCCTGGCAGTGACACGATTAAGCCCAACGTGGATGACAGCAAGGAATATTTCTCCAAACACAATTAG

Retrieve as FASTA  
CDS►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGGCCTCCGGTAACGCGCGCATCGGAAAGCCAGCCCCTGACTTCAAGGCCACAGCGGTGGTTGATGGCGCCTTCAAAGAGGTGAAGCTGTCGGACTACAAAGGGAAGTACGTGGTCCTC
TTTTTCTACCCTCTGGACTTCACTTTTGTGTGCCCCACCGAGATCATCGCGTTCAGCAACCGTGCCGAGGACTTCCGCAAGCTGGGCTGTGAAGTGCTGGGCGTCTCGGTGGACTCTCAG
TTCACCCACCTGGCTTGGATCAACACCCCCCGGAAAGAGGGAGGCTTGGGCCCCCTGAACATCCCCCTGCTTGCTGACGTGACCAGACGCTTGTCTGAGGATTACGGCGTGCTGAAAACA
GATGAGGGCATTGCCTACAGGGGCCTCTTTATCATCGATGGCAAGGGTGTCCTTCGCCAGATCACTGTTAATGATTTGCCTGTGGGACGCTCCGTGGATGAGGCTCTGCGGCTGGTCCAG
GCCTTCCAGTACACAGACGAGCATGGGGAAGTTTGTCCCGCTGGCTGGAAGCCTGGCAGTGACACGATTAAGCCCAACGTGGATGACAGCAAGGAATATTTCTCCAAACACAATTAG

Retrieve as FASTA  
cDNA►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
CTGACGGGAG GACCCCCTTC AGGCTGCTTT GGCCCGATCC TGACTTTAGT GCTGGCCGCC TTTGCTTTCC ATCCGCTATA GTGGCCTCCT TTGTCCTTGC GGGGGAAACC GAGGCCACAG  CCTTGCAGCG CAGGCCGGAT CGCCCGAATC CCCGCCCCCT GCTCGTGCGG GCCTCACTGT CTCCTTTTGG GCTGGGGGCT TGCGACACCG CCCTCCGGCC GACTCGCTCG TGGGGTGCTG  GTGGCAGTGG CTGGGTCACT CGTGCTCTGG TCAGGAGAGC GGGTCTCCGG CAGCCTCCGG GCCTCGTAGA CCGGGTACCC GGGAGGGTGA GGGTTAGTGC TGTCGCCTCC GCCGTGCTGA  CTCAGTCACA GGGCCCAGCA CGCAGCGCGA CCTTGGGTTG GGAGGACAAA GTGTCTTCCC GGGCGCACTG ACCGGGCGGG GGTCTCAGCT TTCAGTCATG GCCTCCGGTA ACGCGCGCAT  CGGAAAGCCA GCCCCTGACT TCAAGGCCAC AGCGGTGGTT GATGGCGCCT TCAAAGAGGT GAAGCTGTCG GACTACAAAG GGAAGTACGT GGTCCTCTTT TTCTACCCTC TGGACTTCAC  TTTTGTGTGC CCCACCGAGA TCATCGCGTT CAGCAACCGT GCCGAGGACT TCCGCAAGCT GGGCTGTGAA GTGCTGGGCG TCTCGGTGGA CTCTCAGTTC ACCCACCTGG CTTGGATCAA  CACCCCCCGG AAAGAGGGAG GCTTGGGCCC CCTGAACATC CCCCTGCTTG CTGACGTGAC CAGACGCTTG TCTGAGGATT ACGGCGTGCT GAAAACAGAT GAGGGCATTG CCTACAGGGG  CCTCTTTATC ATCGATGGCA AGGGTGTCCT TCGCCAGATC ACTGTTAATG ATTTGCCTGT GGGACGCTCC GTGGATGAGG CTCTGCGGCT GGTCCAGGCC TTCCAGTACA CAGACGAGCA  TGGGGAAGTT TGTCCCGCTG GCTGGAAGCC TGGCAGTGAC ACGATTAAGC CCAACGTGGA TGACAGCAAG GAATATTTCT CCAAACACAA TTAGGCTGGC TAACGGATAG TGAGCTTGTG  CCCCTGCCTA GATGCCTGTG CTGGGTGTCC ACCTGTGCCC CCACCTGGGT GCCCTGTGCT GACCCAGGGA AGGCCAGACC TGCCCCTCCA AACTCCACAG TATGGAACCC TGGAGGGCTA  GGCCAAGGCC TTCTCATGCC TCCACCTAGG AGCTGAATAG TGACGCCCTC CCCCAAGCCC ACCCAGCCGC ACACAGGCCT AGAGGTGACC AATAAAGTAT TAGGGAAAGG TGTGACCTCC 
CAAACAAAAA AAAAAAAAAA AGAAAGAAAC AAAGATGGTC AGGCAGACAA AAG 

Retrieve as FASTA