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Entry information : HsDuOx02 (DUOX2 / LNOX2 / THOX2)
Entry ID 3338
Creation 2006-07-26 (Christophe Dunand)
Last sequence changes 2010-10-18 (Myriam Duval (Scipio))
Sequence status complete
Reviewer Catherine Mathe
Last annotation changes 2015-12-10 (Catherine Mathe)
Peroxidase information: HsDuOx02 (DUOX2 / LNOX2 / THOX2)
Name (synonym) HsDuOx02 (DUOX2 / LNOX2 / THOX2)
Class Dual oxidase    [Orthogroup: DuOx001]
Taxonomy Eukaryota Metazoa Chordata Mammalia Hominidae Homo
Organism Homo sapiens (human)    [TaxId: 9606 ]
Cellular localisation N/D
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value HsDuOx02
start..stop		 S start..stop
PtroDuOx02 3152 0 1..1548 1..1547
CfaDuOx02 2775 0 1..1548 1..1571
BtDuOx02 2728 0 1..1548 1..1545
SscDuOx02 2724 0 1..1548 1..1545
Gene structure Fichier Exons►
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 45405540..45405609 68 N° 2 45405185..45405274 88 N° 3 45404752..45404916 163 N° 4 45403966..45404153 186
N° 5 45403582..45403783 200 N° 6 45403309..45403475 165 N° 7 45402848..45402908 59 N° 8 45402626..45402722 95
N° 9 45402088..45402178 89 N° 10 45401722..45401824 101 N° 11 45400987..45401150 162 N° 12 45400245..45400420 174
N° 13 45399543..45399661 117 N° 14 45399030..45399167 136 N° 15 45398726..45398839 112 N° 16 45398323..45398525 201
N° 17 45397841..45398026 184 N° 18 45396338..45396563 224 N° 19 45396158..45396251 92 N° 20 45393991..45394187 195
N° 21 45393403..45393472 68 N° 22 45392953..45393036 82 N° 23 45392248..45392426 177 N° 24 45391860..45392090 229
N° 25 45391581..45391680 98 N° 26 45390207..45390256 48 N° 27 45389812..45389939 126 N° 28 45389436..45389589 152
N° 29 45388026..45388258 231 N° 30 45387635..45387793 157 N° 31 45387134..45387289 154 N° 32 45386761..45386889 127
N° 33 45386348..45386470 121  
complement(join(45386348..45386470,45386761..45386889,45387134..45387289,4538763 5..45387793,45388026..45388258,45389436..45389589,45389812..45389939,45390207..4 5390256,45391581..45391680,45391860..45392090,45392248..45392426,45392953..45393 036,45393403..45393472,45393991..45394187,45396158..45396251,45396338..45396563, 45397841..45398026,45398323..45398525,45398726..45398839,45399030..45399167,4539 9543..45399661,45400245..45400420,45400987..45401150,45401722..45401824,45402088 ..45402178,45402626..45402722,45402848..45402908,45403309..45403475,45403582..45 403783,45403966..45404153,45404752..45404916,45405185..45405274,45405540..454056 09))


exon

Literature and cross-references HsDuOx02 (DUOX2 / LNOX2 / THOX2)
Literature De Deken X., Wang D., Many M.-C., Costagliola S., Libert F., Vassart G., Dumont J.E., Miot F.Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family. J. Biol. Chem. 275:23227-23233(2000).
Protein ref. UniProtKB:   Q9NRD8
DNA ref. GenBank:   NC_000015.9 (45405609..45386348)
Cluster/Prediction ref. UniGene:   Hs.71377
Protein sequence: HsDuOx02 (DUOX2 / LNOX2 / THOX2)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   1548 (1523)
PWM (Da):   %s   175078.87 (172586.5) Transmb domain:   %s   o600-622i1041-1063o1078-1100i1147-1169o1184-1206i1219-1241o (o575-597i1016-1038o1053-1075i1122-1144o1159-1181i1194-1216o)
PI (pH):   %s   7.9 (7.83) Peptide Signal:   %s   cut: 26 range:26-1548
Sequence
Send to BLAST
Send to Peroxiscan
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
MLRARPEALMLLGALLTGSLGPSGSQDALSLPWEVQRYDGWFNNLRHHEpan>RGAVGCRLQRRVPANYADGVYQALEEPQLPNPRRLSNAATRGIAGLPSLHNRTVLGVFFGYHVLSDVVSVETPGCPAEFLNIRIPPGDPVFDPDQRGDVVL
PFQRSRWDPETGRSPSNPRDANQVTGWLDGSAIYGSSHSWSDALRSFSGGQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLAR
QHPDWEDEELFQHARKRVIATYNIAVYEWLPSFLQKTLPEYTGYRPFLDPSISPEFVVASEQFFSTMVPPGVYMRNASCHFRKVLNKGFQSSQALRVCNNYWIRENPNLNSTQEVNELLL
GMASQISELEDNIVVEDLDYWPGPGKFSRTDYVASSIQRGRDMGLPSYSQALLAFGLDIPRNWSDLNPNVDPQVLEATAALYNQDLSQLELLLGGLLESHGDPGPLFSAIVLDQFVRLRD
GDRYWFENTRGLFSKKEIEDIRNTTLRDVLVAVINIDPSALQPNVFVWHGAPCPQPKQLTTDGLPQCAPLTVLDFFEGSSPGFAITIIALCCLPLVSLLLSGVVAYFRGREHKKLQKKLK
ESVKKEAAKDGVPAMEWPGPKERSSPIIIQLLSDRCLQVLNRHLTVLRVVQLQPLQQVNLILSNNRGCRTLLLKIPKEYDLVLLFSSEEERGAFVQQLWDFCVRWALGLHVAEMSEKELF
RKAVTKQQRERILEIFFRHLFAQVLDINQADAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMGSPEDKSRLMFTMYDLDENGFLS
KDEFFTMMRSFIEISNNCLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSELRFTQLCVKGGGGGGGIRDIFKQNISCRVSFITRTPGERSHPQGLGPPAPEAPELGGPGLKK
RFGKKAAVPTPRLYTEALQEKMQRGFLAQKLQQYKRFVENYRRHIVCVAIFSAICVGVFADRAYYGFASPPSDIAQTTLVGIILSRGTAASVSFMFSYILLTMCRNLITFLRETFLNRYV
PFDAAVDFHRWIAMAAVVLAILHSAGHAVNVYIFSVSPLSLLACIFPNVFVNDGSKLPQKFYWWFFQTVGMTGVLLLLVLAIMYVFASHHFRRRSFRGFWLTHHLYILLYALIIHGSYAL
IQLPTFHIYFLVPAIIYGGDKLVSLSRKKVEISVVKAELLPSGVTYLQFQRPQGFEYKSGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAVGPWTTRLREIYSSPKGNGCAGYPL
YLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSLGSQMLCKKIYFIWVTRTQRQFEWLADIIQEVEENDHQDLVSVHIYVTQLAEKFDLRTTMLYICERHFQKVLNRSLF
TGLRSITHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLVNRQDRAHFMHHYENF*

Retrieve as FASTA  
Remarks Complete sequence from genomic (chromo 15, 32 introns), 5 cDNA and 60 ESTs.
DNA ►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGCTCCGTGCAAGACCAGAGGCACTGATGCTCCTGGGAGCTCTTCTGACTGGATCCCTGGGTCCATCGGGCAAGTATCAGGCTCCTCTAGCGGCGGGGTGTTCCCCAGGATCCCTGGGA
GGTGGGGCGGGGAGAGGTGCGGCAAGCGGCTCCCTGAGACTGGAAGGTCATTTCGCCGTGCAGCTCAGCGGGATGGGAAACTTCCCAGTGCGGCCCGACACTTGGGTCCGGTTAGGGGCG
CTCCGCGAGCTGGGGAAGGACTGGCCAAGGCCTTCGTTGCTCGGGAGGGGTAGCTGGGAGCGTAGTGCTGAGGAGGCCCTTCTCTGTGCCCACAGGCGCAGTCAGGACGCACTCTCACTG
CCCTGGGAAGTGCAGCGCTATGACGGCTGGTTTAACAACCTGAGGCACCACGAGCGTGGTGCTGTTGGTGCGTTCTGGGGGCCCGGGCGTGCTGGGGCCGTGGCTCGCGAAGGGCCGGGG
CGCGAAAGGCCCTGAGCGGGGAATCTGCGGGGAACACGCGCCCAGCAGCTCCGCTGCCTACACAGCGCAATCTTATGCGCTCCCGGGGCCAAGAGACCCTTGAGGGAAGGTTCTGTCAGT
GAAGTGGGATGGGGGTTGAGGGAGGCTTAGGGAGAGGTTTGGGGGATCCTAGGGGATGGAGTGCTTAGACAGAGCCCCGCTCCCTGCCTCCGCAGGCGCTGCCGGTTGCAGCGCCGCGTA
CCAGCCAATTACGCCGACGGTGTGTATCAGGCTCTGGAGGAGCCGCAGCTGCCCAACCCGCGCCGGCTCAGCAACGCAGCCACGCGGGGCATAGCCGGCCTGCCGTCGCTCCACAACCGC
ACCGTACTGGGGGTCTTCTTTGGTGAGGGCAAAGGGGGAGACCAGTGGGGTTGATCTGGCGCTCTGCTCAGCCTGGGGGAGGGGCCAGATCCCGTCTGCGAGTCCACAGGAGACCCATCC
GACTCCCAACCACTTCCTCTCTACGCAGCACTTCGAGACTGCCTTCATCTCGGAGAGATTTTGGGATGTTGATACAGAGATATTTGCTCTGTATCTAACCTTTCTCTTACGCCTTATTCC
AACCTAGGGGTGTCACTGGACCCCCATTATAGCTCTTGGGAACTGAGCTCCCCAGCCACCGCTCTCCTCACCGTGTGTTTGTAACCATTTTACCTCCCCCTAGCCCAGAGGGAGGAGGAC
TGACTTGGGGTACCCCTACATAAATTATATCATTTTGATTCTCACAACAGCTTTATGAATTGAGTAGGAAGGGAACTCACTATAGTCTTACTTTGCAGATTAGAAAATTGAGGCTACCTG
GGGCTAACGTGCAGAGCTGGTGGCGGAGCTGGCACTGGGACCTCTGTCTTTTGGCTCCTGAGGACACTTGGAGGCCGCCCTGGCCGTGGGGAGGGCGCAATACGGACGGTTTGTCACGTA
TTGGCGCCCCATGCCCGCAGGCGCTACCATGTTCTTTCCGACGTGGTGAGCGTGGAAACGCCCGGTTGCCCCGCCGAGTTCCTCAACATCCGCATCCCACCTGGAGACCCCGTGTTCGAC
CCCGACCAGCGCGGGGACGTGGTGCTGCCCTTCCAGAGGAGCCGCTGGGACCCCGAGACCGGACGGAGTCCCAGCAACCCCCGGGACCTGGTGAGGCGGGGAAGGCGGCGGGAAGGGACC
GCACCCCAGCCAGGTGGGGCCTGGGCTTCGGGCCTGGCAGGGCCTGGAGGGGAGAGGCGCCCACTCCCCAGCCGCGGACACCCGCCGGGCCCCGGCCTTCCCTGGCCCGCCGCCGCCTCT
CGACCCGGGCTCACCCGCCGCGTGCCCCGCAGGCGCCAACCAGGTGACGGGCTGGCTGGACGGCAGCGCCATCTATGGCTCCTCGCACTCCTGGAGCGACGCGCTGCGGAGCTTCTCGGG
GGGACAGCTGGCGTCGGGGCCCGACCCCGCTTTCCCCCGAGACTCGCAGAACCCCCTGCTCATGTGGGCGGCGCCCGACCCCGCCACCGGGCAGAACGGGCCCCGGGGGCTGTACGGTGA
GGCCACAGGGGCGGGACGGGGCCGGCTGGGGGTCTGCGAGTGTGGGCTCCCCCGATCACGCTACCGCTCGTCTCCTCCCCTGCGCCCCCACGTCGGATGCAGCCCCTTCGGGGCAGAGAG
AGGGAACCGGGAACCCTTCCTGCAGGCGCTGGGCCTGCTCTGGTTCCGCTACCACAACCTGTGGGCGCAGAGGCTGGCCCGCCAGCACCCAGACTGGGAGGACGAGGAGCTGTTCCAGCA
CGCACGCAAGAGGGTCATCGCCACCTACCAGGTCAGCCGTCCGCGCCCCGCGACGTCCTCCCTTCCGCGTGCAAGCCCACGGGAGACTCCGCTGCCCCATGGAGCTCCCCATCTGTGGAC
AACCGCCACCCAGAAACCCCTCCCCAGACAGCCGAGGTCTAGGGAAGCCCCTGTAAATGATAGGGAGGCACGCGCTGTTTATAGGAGAAATCTGGCTGGTGATGATTATTTATCACCTCC
CCAACCCCCACTCCCTCAAATCCCCTGGTTCCTTGTGGGGACAGGCCTCACACTGCTCCTGTCTGAGTTGCTTCTCCCATGATTGACCCTTCCTGGTCTCATCTCCACACGGAAGCCGTC
CTTGGGCTCAGACCCTTCCAGGCCCCACACCATCCAACTTGTGCCTCCCCTCGCCCCTCTCTGCCCCTCAGAAAACATCGCTGTGTATGAGTGGCTGCCCAGCTTCCTGCAGAAAACACT
CCCGGAGTATACAGGTGAGGGAGCGGGGAAGGAGGACACCTGTGCGGAGAATCCTGAGGGGAAGGAGACAGGTGCCTGTGATGGGAGGATGTGGAGGCAAGAAGCCTGTCTCCCCATCAT
CACCGTCTCCTTCCTGCAGGAGATACCGTCCTTTCCTAGACCCCAGCATCTCCCCGGAATTTGTGGTGGCCTCTGAGCAGTTCTTCTCTACCATGGTGCCCCCTGGTGTCTACATGAGGT
GAGGGAGGGGTTGGCAGAGAGGGGCACCACACTAAGAAAGGTGCAGAATGAGCTGCCTTGGGGGCTGGGGCCTTTCACACTCCTTCGCAGTTTCACTAGAGAAGGGGAAGCAAAAATTTG
GGGCCCTGAAACAGAACCCTGGGGTAAGATGTGTAGGCTTAGTAGGGAAATCTCTCCAGCTCTCCTAAGGGCTGAAATTTGGTGGCTGGGTGTAGGATTTGTCTAGCAGCTGGGTCATTC
CCTTCCCTCCTCTCCCCACCCTACCTGGACTAGGAGCGCACTCTATCTTCAGTAAACGCACATCACCAAATCTCTGCCGTGTTCAAGGAAGTTCCTGGGCCACTGCTCAATCCTAGTGAA
CCCCCACTGAGTCCCTCAGCCCACTCAACCCCATCTTTGATTCTTCTCCAAATTCCCTCACCACATCCTTTGTTCTCAATTTCAGAAAAATGCCAGCTGTCATTTCCGGAAGGTCCTGAA
CAAGGGTTTTCAAAGCTCCCAAGCTCTCAGGGTCTGCAACAACTACTGGATTCGGGAGGTCAGACTGGGGTCAGGGTCAGGGGAAGATGGGTCAAGGTCAGTCTCTTCACACAGGCTGGG
AAAAGCAACAATCCCAGTTCTTGAGTGTTGCTGCCCCAGGTTCATGGGAGATGAAGGGTAGAGGAAATTATCCGGGGACAACAGTTCAAGAGAGTCTGGGACTGGCCAAGGGCCCTTTGT
CCTGGGGTACTAAAGTGGTCCAGGCTGAGAGAGACCGAGTTTTGGGTAGAGGCCTATCTTGAGTGCATTGTTTACTTCCAGAAAACCCCAATCTGAACAGTACCCAGGAGGTGAATGAGC
TGCTGCTGGGAATGGCCTCCCAGATTTCGGAGTTGGAGGACAACATAGTGGTTGAAGATCTGAGGGGTGAGCTCAGAGCCAGAAGGGGTGGATGGTAAGGGACCAGGAAGCCTGAGGATC
CCTCTGGGTTCATCAATAGCAGACCTAGGGCGCTCACGATGCAGGAACACAGATACAAACACAGACTTCAAGGAGCCATAAGAAGAAAATGAACTTTGAACTTTTTTTTTTTTTTTGCTT
AATTTACACTTTTGTGTTGCTTTTATTTTAAATTAACTATGTCTGAGTATTGGGGAGGGGTGGTACCACAATCTCTTTGGTGCTTAATTAGGTCTCTAAAGGTTTTCATTCAGCCCTGTC
TTGAAACTAGGGAGGCATAGGACAGGGAATTTACTGCTTGGTGACTAGAACAGTCTTGAGTCTTAGAGGAAGGGTCTTACTGGAAAAACTGGCTCTGATCACCCATGGTGACATTGGCCT
TGCAGCAAGGCAAGGTCAGCATGGGCACAGATCTCATGTGGATCACTGGGGGTAGCCAGGAGGGAAGAACCGTAGTGCCAATAGTCAGATACAAGGCTGCAGGGCAAAAAAGGATGGAGA
GGACAAAGCCCATAGTCTAGTCTTCTCTCCTCTTCAGATATTACTGGCCTGGCCCTGGCAAATTCTCCCGTACAGACTATGTGGCCAGCAGCATCCAACGTGGCCGAGATATGGGGCTGC
CCAGCTATAGCCAGGCCCTGCTGGCCTTTGGGCTGGACATCCCAAGGAACTGGAGTGATCTCAACCCTAATGTGGACCCCCAGGTCAGGAATAGTAATGATAATAATGGCAGCTAAAGCT
TTCCTATGGCAATACTGTTCCAAACCCTTTACATATGTTGACTCATTTAATCTACATAATAATATTGTAAGGTATGTATAATCATTTTCCCCATTTTACTGATGACATAGTTGGTAAATC
ATAGAGGAGGGACTTAAATTCAGCCATCTGATTCCAGAATATATTCCTAACCACTGCATTGTACCATTCCTGCAGGGTGGCTTCTGGGTTGGGTGCCATTGTCCTGTTGCTGCAGGGTCC
CACCCCAAGGGCTGTGTGCCCCTGAAGCTGCTAATCATTGAGGTCAGGCAGGCTGGTGATGGTCACAGGATATGGTCCTAGGGCACCTGACCGTGGTGTTACCGTGGGTAGGGACACACT
GATCCTTCCACCAGACTTGTCCTGCCTGAGGGGGCTTGCCTAAGAAGAGGAAATCAGGCCTGAGCAGCAGCCAGGCAGCGGCTGAGGTTCTGTGCCCGAGGGATGGGGCAACAGTGGCTG
CCCTCCGCAGCAAACATACGCTCACCCCTTATCTCCTGTGGTGCCCCAGGTGTGCTGGAGGCCACAGCTGCCCTGTACAACCAGGACCTATCCCAGCTAGAGCTGCTCCTTGGGGGGCTC
CTGGAGAGCCATGGGGACCCTGGACCCCTGTTCAGTGCCATTGTCCTCGACCAGTTTGTACGGCTGCGGGATGGTGACCGCTACTGGTTTGAGAACACCAGGAATGGGTAAGGCTTGCCT
GGGCCCCCACCTCAGACTGCTCCTCAGCCTGAGCCCCAGACCCTCTGTCTAGCCTTAGACAGCCCCTATGAGCCCTTGATTCCCAGTCAGCCCACCACACCCTTCCCAACCCCTCTGGGT
CTCTCTTTTTTTCTTCTCTTCTCTTTTTCTTTTTCTTTTTCTTTTTTTTTTTTTTTTTTTTTTGAGGCAGAGTCTAGCTTTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTTGGCTCA
ATGCACCCTCTACCTCCCAGGTTCAAGTGATTCTCCTGCATCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCAACATGCCCGGCTAATTTTTTTAAAAAATATTTTTAGTAGAGA
TGGGGTTTCACTATGCTGGTCAGGCTGGTCTCGAACTCCTGACCTCAAGTGATCCACTCGCCTTGGCCTCCCAAAGTGTTGGGATTACAGGCATGAGCCACTGCACCCAGCCCCTCTGGG
TCTCTTTTCTCACCTGGGTCCTTGGGCCTGGGGTTGCTGGAGGCCTGCATCCCCTTCCCATCCCAGTGACTTCTACTTCCTCCAACTTAGGCGCTGTTCTCCAAGAAGGAGATTGAAGAC
ATCCGAAATACCACCCTGCGGGACGTGCTGGTCGCTGTTATCAACATTGACCCCAGTGCCCTGCAGCCCAATGTCTTTGTCTGGCATAAAGGTGAGTGCCGTGGGAGAACACAAGTGAGT
GACAGTGGCCAGAGAAGGATCAAGATTGAGGGTGCGGGGGAATCACTTGGTGCTGTCCAGGGAGCCAGGCACCTTCTGTGTTGGGCTAGGAGGCCTGCATTTGGCTGGCTCCCACAGCAG
GGACCTCAACTAGCACACAAGCTACACCCTACAGTCAAGAAGGGGTGGATGGGGTAGATGCCAAGAGACAGGAAATGAATGGGGACTTTTTGAGGGAGACAGTTTCAGGGAGGTGGGCCT
GGGGAAGACAGATGATACCTTGGTCCTTTATAGGATAGAGGGGAAAGAGGTCTGGCCACATAGCGGGATCCTCAGACTTTGAGGTCTTCCCTGCCCTCTCCCTCAGGTGTGCACCCTGCC
CTCAACCTAAGCAGCTCACAACTGACGGCCTGCCCCAGTGTGCACCCCTGACTGTGCTTGACTTCTTTGAAGGCAGCAGCCCTGGTTTTGCCATCACCATCATTGCTCTCTGCTGCCTTC
CCTTAGGTGAGCTCTTAGGCAGCCTCTCTGCAGACTGGCCCTGCCCCTCATTTCCTGCTGGCCTGAGGGGCTGGCTATTTGGTACCGTTTGAGACCAGGCTCAAGGAACCTCTGGAAGGG
AGGGGCCATAGCCTAAGCCACAGTGGAGCTCTAGGTGAGGGGCTCCCTCCTCACTGTTCCTTCTGATCCACTTCAGTGTGAGTCTGCTTCTCTCTGGAGTGGTGGCCTATTTCCGGGGCC
GAGAACACAAGAAGCTACAAAAGAAACTCAAAGAGAGCGTGAAGAAGGAAGCAGCCAAAGATGGAGTGCCAGGTGAGCAGGGGCTGGGCAGAGGAGGGAGGAGGGACGGAGGAGGGGAGA
GACAGGAGTCTGGGAGAAAGAACCAAGTTACAGAGTGAGAGGAAAGCCAAGGCACCTTTAGGGCGCCTGCTCAGACTCACAGAGGAATTGACCTGAAGGCGGGGACCTGGGGACATCTGC
TGAACTACCCGGCCCAATTATCCCTTCCCCAGCGCGATGGAGTGGCCAGGCCCCAAGGAGAGGAGCAGTCCCATCATCATCCAGCTGCTGTCAGACAGGTGTCTGCAGGTCCTGAACAGG
CATCTCACTGTGCTCCGTGTGGTCCAGCTGCAGCCTCTGCAGCAGGTCAACCTCATCCTGTCCAACAACCGAGGATGCCGCACCCTGCTGCTCAAGATCCCTAAGGAGTATGACCTGGTA
TGGCTCGTCCTGCCTCCCCAGCCTGGGCTGCCCTCACACGACTCCATTATCACAAGCGAGGCCACCCTATCCTCAGCTACAGAGCTCAACTATGACAGCTGATGCTGGGGAGAGGGGCTC
CTTTCAGAGGCCCCCAGACACAACCTGACCCCCTTCGTCCACACACCTGGCCCCAGCCTGGATGGATGGGGAGGAGTTTTCTCTCCTCCCCTCAACCCAAGATCCATTGAGGGGAGGCTG
AAGCAGAAGGTCCAGCGAGCTCCCTGCGTCAGTGCCGCCTTCCTCCCACCCAGGTGTGCTGCTGTTTAGTTCTGAAGAGGAACGGGGCGCCTTTGTGCAGCAGCTATGGGACTTCTGCGT
GCGCTGGGCTCTGGGCCTCCATGTGGCTGAGATGAGCGAGAAGGAGCTATTTAGGAAGGCTGTGACAAAGCAGCAGCGGGAACGCATCCTGGAGATCTTCTTCAGACACCTTTTTGCTCA
GGTGCCATGACCTGTGCCTTTTGGAGATGGGTCCAGCCCCAGAAATGGAGGAAACCTGGGCTGCATAGAACGCCCCTGTGGGTGAACTAAGCTTCCGCTCTATGGCCTGGAGAGAAATAG
CCTTGTTTGAATCCTGGCATTGCCACTTTACTTAGCTCTGTGACCTTAGGCAAGTCACATTATCACTGTTCTGTATCTCTGTTTCCTCATCTATAAAACAGTGATGAAAACTGTATCCAT
CCCATTGCATTGTTGTGAGGATTCGGTGAGATCGTCTACATGAGTGGTACACAGAGGTTGGCCTCTGGACCCGAGAGCATCAGCCTCACCTGGGAACATGTTAGAAATGCACCTACCCAG
TTAGACTGAACCAGGAACTCTGTGGGTGGGGCCTGGCAATCTGTGTTTTAACAAGCTCCCCAGATGATTCAGATACACTCTAATGTTTGAAAAACATTGTTTTATGTACAGTGCTTATTG
GCCCAAGTGCCAGGTATGTTGCAGGCATTTAACAAACGGTTGTGGCCAGGCGCAGTGGCTCATGCCTATAATCCCAGCACTTTGGGAGGCTGAGGCGGGCAGATCACCTAAGGTCAGGAG
TTCGAGACTAGCATGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGACGTGGTGGCTCACACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATC
GCTTGAACCCGGGTGGCGGAGGTTGCAGTGAGCCAAGATCATGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCATCTCAAAAAAACAAACAAAAAACAATAAATGGTTGTTAC
ATGCGACTTTTAAACTTTTTGTGCAATGGGCAAATCATAGGCACATGGCAGCCTTATCTGAATTGGCAAGAGAGCACAGCCCCAGCCCCTTCCTGCCTGTCTACCACCATGTCTCTACAT
CTTCTGTCCCCAGTATAGGCTCTCTCACTTTCCATTCCCCTTAACTTCGCCCTTCCCCTTCCCTACCCCAGCACCATGCCCACTGCATGAAGTTCCCGGTTCTTGGGCCCAGGGAGAAAT
GGGCAGGCTGCTAGAGATTTGATTCCCCCGTCTATAGGACAACAGAGGCCCCAGTCAGTATATCTAAGGATCAGGAGAACCATCAGAGTTTAGCCTTTCTGATTTGGACTTTGGGGAGAT
ATGAAGGGTCACTGAACTGCTTCCAGCATAGGCTTCACCTCCTTCTCTTTCCCTCCCTCTGCTGCTGCCCGAGTGCAGGTGTGCTGGACATCAACCAGGCCGACGCAGGGACCCTGCCCC
TGGACTCCTCCCAGAAGGTGCGGGAGGCCCTGACCTGCGAGCTGAGCAGGGCCGAGTTTGCCGAGTCCCTGGGCCTCAAGCCCCAGGACATGTTTGTGGAGTCCATGTTCTCTCTGGCTG
ACAAGGATGGCAATGGCTACCTGTCCTTCCGAGAGTTCCTGGACATCCTGGTGGTCTTCATGAAAGGTAGGGGGCTGGGAGGTGGCAGGCTATCCAAGAATCCAGGGGTCTTTCAGCAAG
GAGATGACCTGCATTCCCTTTTTTCTTCCCAGGCGCTCCCCAGAGGATAAGTCCCGTCTAATGTTTACCATGTATGACCTGGATGAGAATGGCTTCCTCTCCAAGGACGAATTCTTCACC
ATGATGCGGTATGGGGTGTGCCTTTCTAATCCTGAGACTTCCTGGTGTGTTTCAAACAGGAAAACAGGTCCAGTCAGAGGAGGGCTGGCAAAGAGGCTCTGTGGTCATCTGTGCTGAGAG
GTGGCCTAAACACTACATCCTAAACTCTCAGAGCATCCACCTTCAAATATTTACCTGACTGGCTCCTGCCTCTGGGAGAGTCTCTGTCTGGACTGTCAACACCAGCCAGAAAAGCCTCCC
TAGTTAAAAAACGAAAAAAAAAAACCCAACACCAATATGGCCAACGACAAAAATCCACTAATCCCTTTTGGATGCCCTTGGATCTTTGTGAACTATTTTACGGCACGCCCAACACCGTGC
TCTACCCAGTGAAACAGTGAATGGATGACCTTGGTTGCTGCTCCGCTATTCATCACCATGATAGTCAGGAAGAGAAACGTGGAAGGCTTCTCCATATTCCAACCATTCTTTCTTCCTGCA
TCTTAAGCCCTTTCTGGTTTTGTTGTGCCGGTAAAAAAAAACAGCTTTGTGCTTCTCATTCCTGAAGACAATGAATGCGTCAGTAACACAGCTCCCCTCCATGCCATAAGGGCAGGGCTT
GTTCCCTGTTGAATCCAGCTTCTCTACACTGTGATTGGCACAGGGCAGGCATTTCATACATAACTAACTGAGTAAGACAAAATGAAATAAGTGAGCAAATGAATACAAAGTATAGATGTA
ACAGCCCACATTATTTCAATTTTTCTATCCTGTTAAGCCTTAACATTGCTTTAAGCATTCCCCTTAACTGCTACATTCCTCATATGGTCCAGATACCCCAACTGGACAAGGGCTTCTGAA
AGGGCAAAGCTATTGCAGTCTGTACCTCACTGGGTATGTCACTGCAGGCCCAGCCCGAGGTGAGGCTCAAGGGAATCTAGGAGAGGGTCCCTGCCTCCAAGGGCTGAGTTCCCACCTTCT
TTTTTTGGTTTGTTTGTTTGTTTGTTTTGAGACGGAGTCACTCTGTCACCCAGGCTGGAGTGCAGTGCCACGATCTCGGCTCACTGCAACCTCCACTGCCCAGGTTCAAGTGATTCTCCT
GCCTCAGCCTCCCAAGTAGCTGGAATTACAGGCATGTGCCACCACGTCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTAGTCTCGAACTCCTGACC
TCAGGGGATCAGCCCGCCTCAGCCTCCTAAAGTGCTAGGGTTACAGGCGTGAGCCACCACACCTGGTGAATTCCCACCTTCTTGTCCTGTAACTCAGCGTGTATCTTGCTTACTGTCGGT
GGGACGATGTTTTTAATGTGATGGTTGTGCTTGCTGTGTTTTATGGGCCCAGCATGGCACAGCATTGCTGCCGGACCTACACAAACTTGCATAGTCTGTCTTTTCTGTCCCGAGGCACAA
CCTATGAATAGAGCTTGGCTACTGCAGGTGCCACTGTGGGTGCTATCAGGTTGGGCATGGAGACGCTCCCGCCTGTGCCCCGGGGTGTTGGCACAAGGAAGCAGCAGCATTGCAGCTAGT
TCCCCTCCCTGGCACCTGGCTGCCTGGTGCCCCCACTGGACTATGAAAGGGGGAATCCAGGGGTGATGTGGGAGGCATCAACAGAAGAGAGTGGACAGAGAGCCTGCCACGAGAGAGGGC
CATGCACACCCTGGACACCCCTGCACTCAGTGGACTATCTTCTCAGTTGTAGATGCCCCCTGTTTGAGGGCTGCTTTCTCTGATTGGTCAAGGTCACTTTCAATTCTGTTCTGCCTTTTG
AGTCCATGGCTACCCCACCCAGCTTAGTGTCAGCGGCAGGCTGGATGAGCACCTTCTCAGTGCCATTTCCCGGGTCACTGGTAACCACATTAGATAATCTGGGGCCTGCCCCACCCTGCA
CCTACCCAAGCCTGACCTTGCTGGGTGACAGGCTGCTGTGTCTCTGGTCCTCCTCCAGATATCCTTCATCGAGATCTCCAACAACTGCCTGTCCAAGGCCCAGCTGGCCGAGGTGGTGGA
GTCTATGTTCCGGGAGTCGGGATTCCAGGACAAGGAGGAGCTGACATGGGAGGATTTTCACTTCATGCTGCGGGACCATGACAGCGAGCTCCGCTTCACGCAGCTCTGTGTCAAAGGTGG
AGGTGGAGGTGGAAATGGTGAGTGTGTGAGGAATGGTTGGCGTCAGGGAGGGGGGGCGTGTCCTCAAAATGAGAGTTCCTGGTGGGCAGGACCCAGGTCTTACTCTTTTCTGAGTCCTTG
GTACCTAGTATAGAACCAAGCACATGTAATTGGGATGGCACATGTAGGTGTGCAAGTTGCCTAATGCACAATGATACCCACTGAGGTCAAGGAGCAGGTTGAAATCTATCCTACACACTG
CTCAAAGCCACCGGCATTGCTCTAAGATGTATCTGGCCAGAGGAAGAGGCATTGTTTCTTTTACACAAAGGACCTGCAGGGTTGCATCCACCTAAGAGGATGTCCCCTTTCTTGTGCAAA
GTTGCCACATTGTCTGCCCTGTGTACAGTGAGTGCTTAGTCTAGGGAATGAGGGAAACAGGACTCGAGTCAGAGATCTGGACATGACTTTCCCAGAAGGGAGGAGGGCACAGTCTCCCAT
CCTACCCCACTGCCCTTGTGGGGAAGCCAGTCCTGCCTCTTGTTCTTTTCTCTAGGTGTATTAGAGATATCTTTAAACAAAACATCAGCTGTCGAGTCTCGTTCATCACTCGGACACCTG
GGGAGCGGTGAGCAGGAATGGGGCTCTGGCAGGTTGGCCTGGCTGAGCCCCCTGCAGAGAAATGAAGGGAGTAGGACTGGCTGATCAGCCCCTGGTAAAATCAGGCATTTGCCCTTTGAA
AGTAGCTCATGGTAGCACAAACATTCCAGCTGCCTCTCTCACCCTATGCTGCTCGGATGCTTGGCTCTCTCCCTGCTGCTCCAGGCCAGAATCATTCTACAAAACAAATCATGAGATCCT
ATTAATTCATTTTGTGCCTTGCCCCCTGCCTGGTACCAGGAGCCACTCCCTACCTCTACCCCATGCTCTGCCCAGGGAGTTGTTCTCCTGGCTGCAAAGACAAGGGGAGAACAGCCCCAT
TTCTTTTTCTCAGCTCTCCCACCCCCAGGGACTGGGGCCCCCTGCCCCAGAAGCCCCAGAGCTGGGAGGCCCTGGACTGAAGAAGAGGTTTGGCAAAAAGTGAGTGTCTCCCAAATCCCT
GGGCCCAAAGAGACATGGAGAGAAGTCTTAGGGTCCCTAGGCCCCACCCACATATCCTTGACATATAAGCGACCATCCTGAGTCTCATTCCATTTGTTCCTGACCTGACTGAGAGGTTAC
AGTGTTGAATGACTTTTCATCCTCTTCCAGCCTCTGCACCCCATTCTTCAGGCAAGGGTCCTGGCTCAACAGGATGATAGTAAGGGGTCTCCTGGCTCCTGCCTGCTTTGGGCACAGCCT
TGAGGCCTGTGCTGGGATCAGGAAGAAAGAAGGATAAAACAGACAGGAGGAGGGGGAGTAGCAGGGAGACAGTGAGTGGGTGGATGGAGCAAAGACAGAAGTAAAGGGTTGGAGGAGGAA
GAAGCCCCCAGATTGCTTTTTTCCATTCATCTGTTGTGGCCCATCCTGATGCCTGCCAGATCCCCAGGTCACCTTTCATGGAGTGGCATTAAGGGAAGGCCAGAGGGCCCTTACCACACT
GCTGCCCTGCCTCCCCTTGCTATAGGGGGCAGCAGTGCCCACTCCCCGGCTGTACACAGAGGCGCTGCAAGAGAAGATGCAGCGAGGCTTCCTAGCCCAAAAGCTGCAGCAGTACAAGCG
CTTCGTGGAGAACTACCGGAGGCACATCGTGTGTGTGGCAATCTTCTCGGCCATCTGTGTTGGCGTGTTTGCAGATCGTGCTTACTGTAAGAGTTCCAGGCTGTGGGCAGTGGGTAGGGA
GCAGGCTCTGACCCTTGGAGAGGAGTGGAAAGCCCTCTGATCCTAAGAGTCTGCATGGGAGAGCCCAGGGCTCGGGACCTTGGCCACCTGTGCCAAGCTGATGTAACCTCACTCCGGCCC
CAGACACTATGGCTTTGCCTCGCCACCCTCGGACATTGCACAGACCACCCTCGTGGGCATCATCCTGTCACGAGGCACGGCGGCCAGCGTCTCCTTCATGTTCTCTTATATCTTGCTCAC
CATGTGCCGCAACCTCATAACCTTCCTGCGAGAGACTTTCCTCAACCGCTATGTGCCTTTTGATGCCGCAGTGGACTTCCACCGCTGGATCGCCATGGCTGCTGTTGTCCTGGCCAGTAC
GTGACTCCCAGGCTTCTTCCTCTTTGCTGCAGCACCCTGGGTCTAGTTGGGGGAAACAGTGGGGAGATGGAACTCCTTATACCTCCATCTCTCCTCCCTATGCCTCCTCTCTCCCTCAGG
ATCGGAGGTAGAGTCTGTCCTGGTTGGCATCTCTAACAGGGTCTGTCTCTTCCAGTTTTTTGCACAGTGCTGGCCACGCAGTCAATGTCTACATCTTCTCAGTCAGCCCACTCAGCCTGC
TGGCCTGCATATTCCCCAACGTCTTTGTGAATGATGGGTCAGTTCTGGGGATGGTTTCTCCTGGGACTCATAGGGTGGGCCCAAGGGTATAATAGAAAAAGAAATAGGCAGGCCGGGCGC
GGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAA
AATTAGCCGGGCGTGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCATGAACCCAAGAGGCGGAGCTTGCAGTGAGCCGGGATAGCGCCACTGCAGTC
CAGCTTGGGCGAAAGAGTGAGACTCCGTCTCAAAAAAAAAAAAAAAGAAAGAAATAGGCAGGGCACAATGGCTCACACCTGTAAGCCCAACACTTTGGAAGTCTGAGGCAGGAGGATTGC
TTGAGGCCAGGAGTTCCAGACAAGCCTGAACAACAAAGTGAGACTCCATCTGTACAAAAAGTAAAAAGATTAGCGGGGCATTGTGGTACACATCTGTAGTCCCAGCTATTCAGGAGGCTG
AGGCAGGAGGATTGCTTGAGCCCAGGAGTTTTAGGTTGCAGTGAGCCATGATCAGTACCACTGCATTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTTGAAAAAAAAAAAAAGGAAAGA
AATAGACAGTCCCAGACACTCAGCAAGAAGCTCAGTGCTAAGCTAGTCCCCTGGGGGAAGCTGAAAGGTAAATTTCTTGCCTTCAAGAAGGAAGCTGGCTGTGATTGGCCAGGAAAGGTG
TTTGGGAGATGAAGTCAGAGACTCTTTCTCATAGATACCTGACACACAGCTTGCCATCTCTGCCTTCTATCCATTCACTGGACAGACATTTATGCAGCATGTCCCATGTGTCTACCCAGA
TGCCAGAGTAGGGATGTCAAGATACATGCAGTCATTCAACAACTACTTACCGAGATTTGCTGTGTGCCTTGTATTGTTCTAAGCCTAGGGATAGAGCAGTGAATGAAACAAAAATCCCTG
CCCTCATGGAGCTTACAGAATAATGAACCAGGGACTCAAGGAAGCAGGGGTCAACCACAGTAAGAGAGTTCAGGATAACACAGAAGGAAAAATTGCTGAGTACAGAGGGTGGAACCATGG
AAGCCTGGGTGCCAAGTTCCTTGGAGGGATCCCTGGCCAACTGGGTGGAGGCCCCATACCCTCAGCAGTCAGGGCCAGCAGGAAAGGAGTCATGCTGTGTTGTGACAGTGCTGGAGCCCC
TCCTGCCCCAGTCAGAGGCTCAAGGTGCCTTTGCCCCCCAGGTGTCCAAGCTTCCCCAGAAGTTCTATTGGTGGTTCTTCCAGACCGTCCCAGGTAGGAAACGTGGGACCTGGGGGTTCT
GTCTGAGGACTTCTGCTTTTGTCTCCATCTCTCTGTGAATACTCACTTGTCTATACTGGCCATGGGGTCTGTTTCTAGCCTTCAGGACAAGCCCCAGCTCAAATCCCTCCAGGCAGGCTT
TTCTGGGGGCCCCGGAGGGATGAGAGAGGAAGGAGGGAAGGATAGGGGAATGTGCTGTTGTCTTTTCAGCCCAAGCTGAAGTCCTGAGACTACTCACTGGCCCTGTCTTCCTGCCCCCAG
GTGTATGACAGGTGTGCTTCTGCTCCTGGTCCTGGCCATCATGTATGTCTTCGCCTCCCACCACTTCCGCCGCCGCAGCTTCCGGGGCTTCTGGCTGACCCACCACCTCTACATCCTGCT
CTATGCCCTGGTGAGGGACTTCCCTGGGCCAGCCCATGGAGCAGGGAGCTCAGGATGGGACAGGAAGGTGAAAGAGGGAGAATTGGATCCAAGATCTCAGAATGAGACTTTGAGATTTAA
GACCCCAGACCTCAGCCCTATCTCCCCGGCACAGGCCTAGTGCCTGGGCAAGAGGGGATGCCGGGCAGGGGCCTGGCTGGGCCTGAGTTGTACTAACTGGCCGTGTCTCCAGCTCTCATC
ATCCATGGCAGCTATGCTCTGATCCAGCTGCCCACTTTCCACATCTACTTCCTGGTCCCGGCAATCATCTATGGAGGTGACAAGCTGGTGAGCCTGAGCCGGAAGAAGGTGGAGATCAGC
GTGGTGAAGGCGGAGCTGCTGCCCTCAGGTATCAGGCCCAGCCTGACCTGGGTCGGGAGCGACAGAGGCCAAATCTTCAGACATGGGGAGACAGTTCACCAGGTCTCCTGACCCCATCAC
TGCCTCTGACTCTGTCTCCAAAAACAACAACAACAAAAAACCACTCTCGGGGGTTCCTGAAGGTTTCCTGATAGAAGTAGACCCAGAAAGGGCTGTGCTTAGCTCCCAGGAGACTTGCAG
ATGGTGAGAAGTGACCTGAGAAGAGGTGGCTGAACGTGCATACAGAGGGGTTTGAGGATGGGAAAGGGCCCCACATGTGTGGCCTGGGTGCAGGGGAAGTGCAGGGCAGGAAGCCACATA
TGCCTGTCCCATTCCTTCTCTCAGAGACAGGCAAATGCCCAGATTGCCAGTCTGGGTTGTTGAGAGTCAGTGCTGGCCAAAGTCGGGATTGGTATCATCATAGAGGGTGGCAAAAGATGA
TTTTATGTATCTCAGGACTGTCTAACCTTCAGGACTCATGTTGTAAAAAAATTAATCTCATTGCAATGTTATTTCAATTGAGATTACTTAAGGACAAAATCTCAGAGTGGTGTTAGTATG
CCTTTCTACTCTCCAGCACTTGCTGATCTCCTTTTTCAATGAAGAGATCAGGCCTGAGGCTCAGCTATGGTACAAACAGTATCCAGCTAAAATTTGGTAACAAAATATGTTGTCTTCTAT
GTAGGACACATGATACTGGTTTTCCACTTACCTTAGCAATAAAGTTCCCTGCCAAGATTAATTGAATTGGAAAAGTTAGTCAATTTAAAGAAAAGTGTTAGATAAATGATAGTGCAGGAG
GTGTGTAGAAAGGTAACCCTCAAATGGAGGTCTGGTAGCCACTGAGATGGTCCCTGGTGAGCCTGAGTCCCTTTACCCAGCAGGTTGGTATTCAAGGCAGTGGTATGAGGCCTGGGCCTT
CCATGGGAAGAGGGAGTAGAGAGGAGGAGAGGGGCTGGAACAGGGGAGCAGAGAAACCCAGCTCTTGCATTACCTGGGAAACAGAGAAGGGGACCCTCCTACTCCCAGCCCCAGGAGCCC
CGCTTGCTCAGACCATGTGACTACTCCCCAGGCCTCAGGGGTGTGAAGAGGACAGGTGCCTATCAGTCCTCAGGTACCAGGAGCAGGCCTTCTCATCTGTGCTTTTCCCTGTCTATGACC
TCCAGGAGAGTGACCTACCTGCAATTCCAGAGGCCCCAAGGCTTTGAGTACAAGTCAGGACAGTGGGTGCGGATCGCCTGCCTGGCTCTGGGGACCACCGAGTACCACCCCTTCACACTG
ACCTCCGCGCCCCATGAGGACACACTCAGCCTGCACATCCGGGCAGTGGGGCCCTGGACCACTCGCCTCAGGGAGATCTACTCATCCCCAAAGGGCAATGGCTGTGCTGGATACCCAAAG
GTGCCCGTCACTGGGAACCCTGCTTCCGGGCCTCTGGCACTGGCAGAGGATCTCTGCCCTTCCCTATCCTGAGACTAGAAGCTCCAGCCGTCCCAAAGCCAGCCTGGGAGAGGACCGGGG
TGCCTCAGAAAAGACTAGGATGTTCTGTATCCTCCCTCTGCCTGTGTCTCCGTTTCTGGTCTCAGAGCTGGGGCAGGGTCAGGCTCATTTCATCTCCCCCCTCTCTTGGCAGCTCTGTAC
CTTGATGGACCGTTTGGAGAGGGCCATCAGGAGTGGCATAAATTTGAGGTGTCAGTGTTGGTGGGAGGGGGCATTGGGGTCACCCCCTTTGCCTCCATCCTCAAAGACCTGGTCTTCAAG
TCATCCTTGGGCAGCCAAATGCTGTGTAAGAAGGTGAGCATCCCTCCCTCATTCATCAAATGGGGCATAGGTGGCCGAATTGTGACCCGCATCAAGTGGTGGAGCATGAGAGAAAGCTCC
TGGCTCCAGGAACTGAGTCTGAAGGGGTCATTCTTACCCAGTGGTTGAGATGCCAAACTTGGAGGGAGGTTGGTGGTATAGCCAGAAGGGCCTCTGCTGGGACCTGTCAGTTGGAAGCCT
GGGATCAGGCTGGTGGGTCCTGCCACAGCTTTGGTGTCTGCAGGTGGTCTGGGGCTTCCCAGCCTCTCAGGTGAAGGCACCTGGGATCTAGGGAGGCTGAACTGAGCTGGGTCCTGATCT
CCAGCCCTGTGTCCCCAGATATCTACTTCATCTGGGTGACACGGACCCAGCGTCAGTTTGAGTGGCTGGCTGACATCATCCAAGAGGTGGAGGAGAACGACCACCAGGACCTGGTGTCTG
TGCACATTTATGTCACCCAGCTGGCTGAGAAGTTCGACCTCAGGACCACCATGCTAGTATGTCAGGGCCCGCCAGGCAGGGCAACTTGGCGGGCAGATGGATTGGCAGCGTAAGGCAGGA
TGGCCAGGGCAGGTGGGTGGACGGCCAGGCTGAGCTGGCAGGAGGCACAGAGCTGATGGCCTGATCCTCAGCCTCCAGCTCCCTCCCCTCCCCATTCTCTGTCTCTTGGGCTATGTGGGC
TGGCTCGGGCTGAGTGCTGGCCCTGACTGTCTTTGGTCTGACCTGCCCCTGTGCCCCCAGTATACATCTGCGAGCGGCACTTCCAGAAAGTGCTGAACCGGAGTCTGTTCACGGGCCTGC
GCTCCATCACCCACTTTGGCCGTCCCCCCTTCGAGCCCTTCTTCAACTCCCTGCAGGAGGTCCACCCACAGGTCAGTCCCACTCCCTCCCACCCTGGGACTCTGGCCTTCTCCTGCCAGG
ACATCCTGGCCCTGAAGCACCCTGCCACTCTGTTCTGAGCAGAGAACTCCACCCGATTGCCTGGCCCCAGGATGAGGTCAGCTGTTAAAGGGGGACTTCCACCCCCTCCACGTTAAGCCT
CCTCCTCAAGGCCTGGGCTTGAAGCCTTAGTCATTCCAGCCAGGCTCAGGAAGCAGCTTTTCCCAAGGAGAGTGAGCACCTTTAGGCTGCAGGCCCCTCTCTCTCTCCAATCTCCTGACA
GGTGTGCGCAAGATCGGGGTGTTCAGCTGCGGCCCTCCAGGAATGACCAAGAATGTAGAGAAGGCCTGTCAGCTCGTCAACAGGCAGGACCGAGCCCACTTCATGCACCACTATGAGAAC
TTCTGA

Retrieve as FASTA  
CDS►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGCTCCGTGCAAGACCAGAGGCACTGATGCTCCTGGGAGCTCTTCTGACTGGATCCCTGGGTCCATCGGGCAGTCAGGACGCACTCTCACTGCCCTGGGAAGTGCAGCGCTATGACGGC
TGGTTTAACAACCTGAGGCACCACGAGCGTGGTGCTGTTGGCTGCCGGTTGCAGCGCCGCGTACCAGCCAATTACGCCGACGGTGTGTATCAGGCTCTGGAGGAGCCGCAGCTGCCCAAC
CCGCGCCGGCTCAGCAACGCAGCCACGCGGGGCATAGCCGGCCTGCCGTCGCTCCACAACCGCACCGTACTGGGGGTCTTCTTTGGCTACCATGTTCTTTCCGACGTGGTGAGCGTGGAA
ACGCCCGGTTGCCCCGCCGAGTTCCTCAACATCCGCATCCCACCTGGAGACCCCGTGTTCGACCCCGACCAGCGCGGGGACGTGGTGCTGCCCTTCCAGAGGAGCCGCTGGGACCCCGAG
ACCGGACGGAGTCCCAGCAACCCCCGGGACCTGGCCAACCAGGTGACGGGCTGGCTGGACGGCAGCGCCATCTATGGCTCCTCGCACTCCTGGAGCGACGCGCTGCGGAGCTTCTCGGGG
GGACAGCTGGCGTCGGGGCCCGACCCCGCTTTCCCCCGAGACTCGCAGAACCCCCTGCTCATGTGGGCGGCGCCCGACCCCGCCACCGGGCAGAACGGGCCCCGGGGGCTGTACGCCTTC
GGGGCAGAGAGAGGGAACCGGGAACCCTTCCTGCAGGCGCTGGGCCTGCTCTGGTTCCGCTACCACAACCTGTGGGCGCAGAGGCTGGCCCGCCAGCACCCAGACTGGGAGGACGAGGAG
CTGTTCCAGCACGCACGCAAGAGGGTCATCGCCACCTACCAGAACATCGCTGTGTATGAGTGGCTGCCCAGCTTCCTGCAGAAAACACTCCCGGAGTATACAGGATACCGTCCTTTCCTA
GACCCCAGCATCTCCCCGGAATTTGTGGTGGCCTCTGAGCAGTTCTTCTCTACCATGGTGCCCCCTGGTGTCTACATGAGAAATGCCAGCTGTCATTTCCGGAAGGTCCTGAACAAGGGT
TTTCAAAGCTCCCAAGCTCTCAGGGTCTGCAACAACTACTGGATTCGGGAGAACCCCAATCTGAACAGTACCCAGGAGGTGAATGAGCTGCTGCTGGGAATGGCCTCCCAGATTTCGGAG
TTGGAGGACAACATAGTGGTTGAAGATCTGAGGGATTACTGGCCTGGCCCTGGCAAATTCTCCCGTACAGACTATGTGGCCAGCAGCATCCAACGTGGCCGAGATATGGGGCTGCCCAGC
TATAGCCAGGCCCTGCTGGCCTTTGGGCTGGACATCCCAAGGAACTGGAGTGATCTCAACCCTAATGTGGACCCCCAGGTGCTGGAGGCCACAGCTGCCCTGTACAACCAGGACCTATCC
CAGCTAGAGCTGCTCCTTGGGGGGCTCCTGGAGAGCCATGGGGACCCTGGACCCCTGTTCAGTGCCATTGTCCTCGACCAGTTTGTACGGCTGCGGGATGGTGACCGCTACTGGTTTGAG
AACACCAGGAATGGGCTGTTCTCCAAGAAGGAGATTGAAGACATCCGAAATACCACCCTGCGGGACGTGCTGGTCGCTGTTATCAACATTGACCCCAGTGCCCTGCAGCCCAATGTCTTT
GTCTGGCATAAAGGTGCACCCTGCCCTCAACCTAAGCAGCTCACAACTGACGGCCTGCCCCAGTGTGCACCCCTGACTGTGCTTGACTTCTTTGAAGGCAGCAGCCCTGGTTTTGCCATC
ACCATCATTGCTCTCTGCTGCCTTCCCTTAGTGAGTCTGCTTCTCTCTGGAGTGGTGGCCTATTTCCGGGGCCGAGAACACAAGAAGCTACAAAAGAAACTCAAAGAGAGCGTGAAGAAG
GAAGCAGCCAAAGATGGAGTGCCAGCGATGGAGTGGCCAGGCCCCAAGGAGAGGAGCAGTCCCATCATCATCCAGCTGCTGTCAGACAGGTGTCTGCAGGTCCTGAACAGGCATCTCACT
GTGCTCCGTGTGGTCCAGCTGCAGCCTCTGCAGCAGGTCAACCTCATCCTGTCCAACAACCGAGGATGCCGCACCCTGCTGCTCAAGATCCCTAAGGAGTATGACCTGGTGCTGCTGTTT
AGTTCTGAAGAGGAACGGGGCGCCTTTGTGCAGCAGCTATGGGACTTCTGCGTGCGCTGGGCTCTGGGCCTCCATGTGGCTGAGATGAGCGAGAAGGAGCTATTTAGGAAGGCTGTGACA
AAGCAGCAGCGGGAACGCATCCTGGAGATCTTCTTCAGACACCTTTTTGCTCAGGTGCTGGACATCAACCAGGCCGACGCAGGGACCCTGCCCCTGGACTCCTCCCAGAAGGTGCGGGAG
GCCCTGACCTGCGAGCTGAGCAGGGCCGAGTTTGCCGAGTCCCTGGGCCTCAAGCCCCAGGACATGTTTGTGGAGTCCATGTTCTCTCTGGCTGACAAGGATGGCAATGGCTACCTGTCC
TTCCGAGAGTTCCTGGACATCCTGGTGGTCTTCATGAAAGGCTCCCCAGAGGATAAGTCCCGTCTAATGTTTACCATGTATGACCTGGATGAGAATGGCTTCCTCTCCAAGGACGAATTC
TTCACCATGATGCGATCCTTCATCGAGATCTCCAACAACTGCCTGTCCAAGGCCCAGCTGGCCGAGGTGGTGGAGTCTATGTTCCGGGAGTCGGGATTCCAGGACAAGGAGGAGCTGACA
TGGGAGGATTTTCACTTCATGCTGCGGGACCATGACAGCGAGCTCCGCTTCACGCAGCTCTGTGTCAAAGGTGGAGGTGGAGGTGGAAATGGTATTAGAGATATCTTTAAACAAAACATC
AGCTGTCGAGTCTCGTTCATCACTCGGACACCTGGGGAGCGCTCCCACCCCCAGGGACTGGGGCCCCCTGCCCCAGAAGCCCCAGAGCTGGGAGGCCCTGGACTGAAGAAGAGGTTTGGC
AAAAAGGCAGCAGTGCCCACTCCCCGGCTGTACACAGAGGCGCTGCAAGAGAAGATGCAGCGAGGCTTCCTAGCCCAAAAGCTGCAGCAGTACAAGCGCTTCGTGGAGAACTACCGGAGG
CACATCGTGTGTGTGGCAATCTTCTCGGCCATCTGTGTTGGCGTGTTTGCAGATCGTGCTTACTACTATGGCTTTGCCTCGCCACCCTCGGACATTGCACAGACCACCCTCGTGGGCATC
ATCCTGTCACGAGGCACGGCGGCCAGCGTCTCCTTCATGTTCTCTTATATCTTGCTCACCATGTGCCGCAACCTCATAACCTTCCTGCGAGAGACTTTCCTCAACCGCTATGTGCCTTTT
GATGCCGCAGTGGACTTCCACCGCTGGATCGCCATGGCTGCTGTTGTCCTGGCCATTTTGCACAGTGCTGGCCACGCAGTCAATGTCTACATCTTCTCAGTCAGCCCACTCAGCCTGCTG
GCCTGCATATTCCCCAACGTCTTTGTGAATGATGGGTCCAAGCTTCCCCAGAAGTTCTATTGGTGGTTCTTCCAGACCGTCCCAGGTATGACAGGTGTGCTTCTGCTCCTGGTCCTGGCC
ATCATGTATGTCTTCGCCTCCCACCACTTCCGCCGCCGCAGCTTCCGGGGCTTCTGGCTGACCCACCACCTCTACATCCTGCTCTATGCCCTGCTCATCATCCATGGCAGCTATGCTCTG
ATCCAGCTGCCCACTTTCCACATCTACTTCCTGGTCCCGGCAATCATCTATGGAGGTGACAAGCTGGTGAGCCTGAGCCGGAAGAAGGTGGAGATCAGCGTGGTGAAGGCGGAGCTGCTG
CCCTCAGGAGTGACCTACCTGCAATTCCAGAGGCCCCAAGGCTTTGAGTACAAGTCAGGACAGTGGGTGCGGATCGCCTGCCTGGCTCTGGGGACCACCGAGTACCACCCCTTCACACTG
ACCTCCGCGCCCCATGAGGACACACTCAGCCTGCACATCCGGGCAGTGGGGCCCTGGACCACTCGCCTCAGGGAGATCTACTCATCCCCAAAGGGCAATGGCTGTGCTGGATACCCAAAG
CTGTACCTTGATGGACCGTTTGGAGAGGGCCATCAGGAGTGGCATAAATTTGAGGTGTCAGTGTTGGTGGGAGGGGGCATTGGGGTCACCCCCTTTGCCTCCATCCTCAAAGACCTGGTC
TTCAAGTCATCCTTGGGCAGCCAAATGCTGTGTAAGAAGATCTACTTCATCTGGGTGACACGGACCCAGCGTCAGTTTGAGTGGCTGGCTGACATCATCCAAGAGGTGGAGGAGAACGAC
CACCAGGACCTGGTGTCTGTGCACATTTATGTCACCCAGCTGGCTGAGAAGTTCGACCTCAGGACCACCATGCTATACATCTGCGAGCGGCACTTCCAGAAAGTGCTGAACCGGAGTCTG
TTCACGGGCCTGCGCTCCATCACCCACTTTGGCCGTCCCCCCTTCGAGCCCTTCTTCAACTCCCTGCAGGAGGTCCACCCACAGGTGCGCAAGATCGGGGTGTTCAGCTGCGGCCCTCCA
GGAATGACCAAGAATGTAGAGAAGGCCTGTCAGCTCGTCAACAGGCAGGACCGAGCCCACTTCATGCACCACTATGAGAACTTCTGA

Retrieve as FASTA