Entry information : HsPxd01
| Entry ID | 3355 |
|---|---|
| Creation | 2007-01-10 (Marcel Zamocky) |
| Last sequence changes | 2010-11-11 (Marcel Zamocky) |
| Sequence status | complete |
| Reviewer | Catherine Mathe |
| Last annotation changes | 2015-12-10 (Catherine Mathe) |
Peroxidase information: HsPxd01
| Name | HsPxd01 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Class | Peroxidasin [Orthogroup: Pxd001] | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Taxonomy | Eukaryota Metazoa Chordata Mammalia Hominidae Homo | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Organism | Homo sapiens (human) [TaxId: 9606 ] | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cellular localisation | Apoplastic |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Tissue types | Brain chondrosarcoma Embryonic tissue Eye Lung Skin Spleen |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inducers | melanoma retinoblastoma |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Repressor | N/D |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Best BLASTp hits |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Gene structure Fichierperl './assets/cgi-bin/draw_exon.pl' '3355' 'complement(join(1637976..1638095,1639180..1639293,1642618..1642750,1643074..1643194,1647140..1647348,1648390..1648524,1651944..1653447,1657400..1657557,1658172..1658280,1664653..1664809,1665844..1665956,1667377..1667535,1668730..1668846,1669986..1670258,1677415..1677584,1680699..1680816,1683965..1684134,1687428..1687499,1687852..1687923,1691404..1691475,1695700..1695771,1696835..1696906,1748028..1748227))' |
Exons►
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Literature and cross-references HsPxd01
| Literature | REFERENCE 1. Mammalian Gene Collection Program Team. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002);
REFERENCE 2. Zamocky M., Jakopitsch C., Furtmüller P.G., Dunand C., Obinger C. The peroxidase-cyclooxygenase superfamily: reconstructed evolution of critical enzymes of the innate immune system. Proteins (2008) 72:589-605; REFERENCE 3. Cheng G., Salerno J.C., Cao Z., Pagano P.J., Lambeth J.D. (2008) Identification and characterization of VPO1, a new animal heme-containing peroxidase. Free Radic. Biol. Med. 45:1682-1694. |
|---|---|
| Protein ref. | GenPept: 109150416 UniProtKB: Q92626 |
| DNA ref. | GenBank: NC_000002.11 (1748227..1637979) |
| mRNA ref. | GenBank: NM_012293.1 |
| EST ref. | GenBank: BQ681443.1 CX164473.1 [5' end] BQ014722.1 [3' end] |
| Cluster/Prediction ref. | UniGene: Hs.332197 |
Protein sequence: HsPxd01
| Sequence Properties first value : protein second value (mature protein) |
|
||||||||||||
| Sequence Send to BLAST Send to Peroxiscan |
|
||||||||||||
| Remarks | Complete sequence from genomic (chromosome 2, 22 introns), 9 cDNA and 719 ESTs. Most ESTs cover the peroxidase domain (down to 3´end). Synonyms: Vascular peroxidase 1; melanoma-associated antigen MG50; p53-responsive gene 2 protein. Uniprot entry: 2 isoforms produced by alternative splicing. Fusion protein: 62-315 leucine-rich repeat,246-609 IGcam 4 immunoglobulin-cell adhesion molecule domains, 739-1292 heme peroxidase domain, 1419-1470 von Willebrand factor type C domain | ||||||||||||
| DNA ► Send to BLAST |
|
||||||||||||
| CDS► Send to BLAST |
|
||||||||||||
| cDNA► Send to BLAST |
|
||||||||||||
